ATP2B2 and SLC9A3R2

Number of citations of the paper that reports this interaction (PubMedID 11786550)
28

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		ATP2B2	SLC9A3R2
Description		ATPase plasma membrane Ca2+ transporting 2	SLC9A3 regulator 2
Image		No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Plasma Membrane Integral Component Of Membrane Cell Junction Intracellular Membrane-bounded Organelle Extracellular Exosome Presynapse Postsynaptic Density Membrane Glutamatergic Synapse GABA-ergic Synapse	Nucleus Plasma Membrane Focal Adhesion Endomembrane System Apical Plasma Membrane Extracellular Exosome
	Molecular Function	Calcium-transporting ATPase Activity Protein Binding Calmodulin Binding ATP Binding Cation-transporting ATPase Activity PDZ Domain Binding Metal Ion Binding Calcium-transporting ATPase Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Calcium-transporting ATPase Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration	Signaling Receptor Binding Protein Binding Beta-catenin Binding Protein C-terminus Binding Phosphatase Binding Cadherin Binding Molecular Adaptor Activity
	Biological Process	Calcium Ion Transport Cellular Calcium Ion Homeostasis Sensory Perception Of Sound Neuron Differentiation Ion Transmembrane Transport Regulation Of Cytosolic Calcium Ion Concentration Calcium Ion Transmembrane Transport Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Regulation Of Cardiac Conduction	Protein-containing Complex Assembly
Pathways		Reduction of cytosolic Ca++ levels Ion homeostasis Ion transport by P-type ATPases
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Cognitive decline rate in late mild cognitive impairment ( 26252872) Manganese levels ( 26025379) Metabolite levels ( 19043545)	Diastolic blood pressure ( 27841878 30578418) Pulse pressure ( 30578418) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		8 interacting genes: DLG1 DLG2 DLG4 ERBIN PDZD11 PRKCA SLC9A3R2 SNTA1	37 interacting genes: ABCC4 ACTN4 ADORA2B ADRB2 ATP2B2 CFTR EZR KCNJ1 LPAR1 LPAR2 P2RY1 PDGFRB PDPK1 PDZK1 PLCB3 PODXL PRKACA PRKCA PTEN PTH1R RDX RPS6KA1 SGK1 SGK3 SIAH1 SLC22A4 SLC22A5 SLC22A9 SLC26A3 SLC34A1 SLC9A3 SLCO1A2 SLCO3A1 SRY TAZ TBC1D10A WWTR1
Entrez ID		491	9351
HPRD ID		00160	05946
Ensembl ID		ENSG00000157087	ENSG00000065054
Uniprot IDs		A0A024R2E4 Q01814 Q4LE63	Q15599
PDB IDs			2D11 2HE4 2OCS 4P0C
Enriched GO Terms of Interacting Partners?
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