NRF1 and PLXDC1

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		NRF1	PLXDC1
Description		nuclear respiratory factor 1	plexin domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Extracellular Exosome	Extracellular Region Cytoplasm Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Dendrite Neuronal Cell Body Receptor Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Regulation Of Transcription By RNA Polymerase II Mitochondrion Organization Positive Regulation Of Transcription By RNA Polymerase II	Angiogenesis Spinal Cord Development
Pathways		PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Transcriptional activation of mitochondrial biogenesis
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Obesity-related traits ( 23251661) Platelet count ( 27863252) Plateletcrit ( 27863252) Red cell distribution width ( 28957414) Response to antidepressants and depression ( 27622933)	Asthma ( 31619474)
Interacting Genes		13 interacting genes: CSNK2A1 DYNLL1 FHL2 LHX4 MAFF PARP1 PLXDC1 POGZ PPARGC1A PPRC1 SIAH2 SP4 TRAF2	2 interacting genes: NID1 NRF1
Entrez ID		4899	57125
HPRD ID		02930	08439
Ensembl ID		ENSG00000106459	ENSG00000161381
Uniprot IDs		A0A024R770 A0A024R774 Q16656	Q8IUK5
PDB IDs
Enriched GO Terms of Interacting Partners?
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