NDUFAB1 and SMYD3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		NDUFAB1	SMYD3
Description		NADH:ubiquinone oxidoreductase subunit AB1	SET and MYND domain containing 3
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Mitochondrial Matrix Mitochondrial Large Ribosomal Subunit Mitochondrial Membrane	Nucleus Nucleoplasm Cytosol
	Molecular Function	Acyl Binding Acyl Carrier Activity Fatty Acid Binding Calcium Ion Binding Protein Binding NADH Dehydrogenase (ubiquinone) Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding RNA Polymerase II Complex Binding RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Fatty Acid Biosynthetic Process Protein Lipoylation Mitochondrial Respiratory Chain Complex I Assembly	Nucleosome Assembly Negative Regulation Of Protein Kinase Activity Myotube Cell Development Positive Regulation Of Peptidyl-serine Phosphorylation Histone Lysine Methylation Establishment Of Protein Localization Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Dexamethasone Stimulus
Pathways		Glyoxylate metabolism and glycine degradation Respiratory electron transport Complex I biogenesis Mitochondrial Fatty Acid Beta-Oxidation	PKMTs methylate histone lysines
Drugs		NADH
Diseases
GWAS		Bipolar disorder ( 17554300)	Bipolar disorder ( 31043756) Blood metabolite levels ( 26401656) Coffee consumption ( 31046077) Fractional exhaled nitric oxide (childhood) ( 24315451) Obesity-related traits ( 23251661) Post bronchodilator FEV1 ( 26634245) Response to serotonin reuptake inhibitors in non-psychotic unipolar depression ( 26348319) Systemic lupus erythematosus ( 29848360) Upper eyelid sagging severity ( 24869959)
Interacting Genes		4 interacting genes: MRPL23 NT5C3A RBM18 SMYD3	17 interacting genes: APP CAMK2B CYP39A1 EED EZH2 H3-4 H3-5 HELZ HSP90AA1 NDUFAB1 NFYB PBX2 POLR2K SCCPDH TRIT1 VANGL1 ZNF557
Entrez ID		4706	64754
HPRD ID		11951	12297
Ensembl ID		ENSG00000004779	ENSG00000185420
Uniprot IDs		O14561	B3KN46 Q9H7B4
PDB IDs		2DNW 5OOL 5OOM 5XTB 5XTC 5XTD 5XTH 5XTI 6ODD	3MEK 3OXF 3OXG 3OXL 3PDN 3QWP 3RU0 5CCL 5CCM 5EX0 5EX3 5HI7 5HQ8 5V37 5XXD 5XXG 5XXJ 5YJO 6IJL
Enriched GO Terms of Interacting Partners?
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