NEB and KLHL41

Number of citations of the paper that reports this interaction (PubMedID 30986853)
2

Data Source:
BioGRID (two hybrid)

		NEB	KLHL41
Description		nebulin	kelch like family member 41
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Actin Cytoskeleton Z Disc Extracellular Exosome	Ruffle Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Cytosol Cytoskeleton Plasma Membrane Pseudopodium M Band Cul3-RING Ubiquitin Ligase Complex Sarcoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Structural Constituent Of Muscle Actin Filament Binding	Protein Binding
	Biological Process	Muscle Organ Development Somatic Muscle Development Muscle Filament Sliding Regulation Of Actin Filament Length Muscle Fiber Development Cardiac Muscle Thin Filament Assembly	Striated Muscle Contraction Protein Ubiquitination Myofibril Assembly Regulation Of Lateral Pseudopodium Assembly Skeletal Muscle Cell Differentiation Post-translational Protein Modification Sarcomere Organization Regulation Of Myoblast Differentiation Skeletal Muscle Fiber Development Regulation Of Myoblast Proliferation Regulation Of Skeletal Muscle Cell Differentiation
Pathways		Striated Muscle Contraction	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases		Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM) Nemaline myopathy
GWAS		Asparaginase-induced acute pancreatitis in acute lymphoblastic leukemia (onset time) ( 27114598) Creatine kinase levels ( 29403010) Estimated glomerular filtration rate ( 31152163 31451708) Letter-number span reordering ( 31596458) Rapid automised naming of letters ( 30741946) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		18 interacting genes: ABI1 ACTG2 ACTN4 APC CALM1 DES KLHL41 MTDH MYPN TMOD1 TMOD4 TPM1 TPM2 TRIM55 TRIM63 TTN XIRP1 XIRP2	7 interacting genes: CENPF IFRD1 NEB NRAP RBM4 RCHY1 SLC2A4
Entrez ID		4703	10324
HPRD ID		01196	07610
Ensembl ID		ENSG00000183091	ENSG00000239474
Uniprot IDs		P20929 Q05C45 Q96MF8	O60662
PDB IDs		1ARK 1NEB
Enriched GO Terms of Interacting Partners?
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