NCF4 and PRKDC

  • Number of citations of the paper that reports this interaction (PubMedID 9914162)
  • 3
  • Data Source:
  • BioGRID (enzymatic study)

NCF4

PRKDC

Description neutrophil cytosolic factor 4 protein kinase, DNA-activated, catalytic subunit
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever or eczema) ( 29679657)
  • Atopic dermatitis ( 22197932)
  • Crohn's disease ( 28067908)
  • Eosinophil counts ( 27863252)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Eosinophil percentage of white cells ( 27863252)
  • Inflammatory bowel disease ( 27569725)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Multiple sclerosis ( 31604244 24076602)
  • Multiple sclerosis and triglyceride levels (pleiotropy) ( 26920376)
  • Neutrophil percentage of granulocytes ( 27863252)
  • Sum eosinophil basophil counts ( 27863252)
Interacting Genes 10 interacting genes: CORO1A CYBA CYBB MSN NCF1 NCF2 PRKCD PRKDC TXN XRCC6 89 interacting genes: ABL1 AICDA AKT1 AKT2 AP1B1 ATM ATRIP BRCA1 C1D CASP3 CCNB1 CHEK1 CHEK2 CHUK CIB1 CLK1 CTDP1 DCAF1 DCLRE1C E4F1 EIF2S2 EIF4EBP1 EP300 ERG FH GSK3A GSK3B GZMB H1-1 H1-2 H2AX HDAC3 HMGB1 HMGB2 HNRNPA1 HNRNPC HOXC4 HSF1 HSP90AA1 IKBKB ILF2 JUN KAT2A LIG4 LYN MAPK8 MBP MKNK1 MRE11 MTNR1B NBN NCF1 NCF2 NCF4 NCOA6 NR3C1 PARP1 PCNA PDX1 PGR POU2F1 PPP6C PPP6R1 PPP6R3 PRKCD RAD17 RASSF1 RBBP8 RPA1 RPA2 SGO1 SP1 SRF SUMO2 THRA THRB TOP1 TP53 TREX1 UBE2I USF1 WRN XPA XRCC4 XRCC5 XRCC6 YWHAG YWHAQ ZBTB7A
Entrez ID 4689 5591
HPRD ID 03289 02941
Ensembl ID ENSG00000100365 ENSG00000253729
Uniprot IDs A0A494BZS1 Q15080 P78527
PDB IDs 1H6H 1OEY 1W6X 1W70 1Z9Q 2DYB 5LUQ 5W1R 5Y3R
Enriched GO Terms of Interacting Partners?
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