PPP1R12A and PRKG1

  • Number of citations of the paper that reports this interaction (PubMedID 10567269)
  • 139
  • Data Source:
  • HPRD (two hybrid, in vitro)

PPP1R12A

PRKG1

Description protein phosphatase 1 regulatory subunit 12A protein kinase cGMP-dependent 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
  • 3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134)
  • Alcohol misuse (trauma interaction) ( 28265120)
  • Asthma ( 21907864)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Body mass index ( 28552196)
  • Chlamydia trachomatis seropositivity ( 29967566)
  • Colorectal cancer or advanced adenoma ( 30510241)
  • Coronary artery disease ( 29212778)
  • Gait rhythm ( 26219847)
  • Height ( 28552196 31562340)
  • Interferon alpha levels in systemic lupus erythematosus ( 25338677)
  • Logical memory (delayed recall) in normal cognition ( 29274321)
  • Loneliness (multivariate analysis) ( 27629369)
  • Mammographic density (non-dense area) ( 25342443)
  • Mitochondrial DNA copy number ( 30704525)
  • Obesity-related traits ( 23251661)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 30285260)
  • Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes 13 interacting genes: ATXN10 CDKN3 DMPK IL16 ILK KDM1A MPRIP PRKG1 RHOA ROCK1 ROCK2 SETD7 YWHAG 35 interacting genes: ANXA7 AR CFTR CREB1 CRIP2 FAM124A FHOD1 GABRR1 GKAP1 GTF2I HDAC1 IRAG1 ITPR1 LASP1 LMO2 NPR1 PDE5A PLCB3 PPP1R12A PPP1R12B PPP1R17 PRKCA RAF1 RGS2 RYR1 SELL SEPTIN3 SF1 SPP1 TNNT1 TRIM39-RPP21 TRPC3 VASP WDR77 ZNF646
Entrez ID 4659 5592
HPRD ID 03606 08910
Ensembl ID ENSG00000058272 ENSG00000185532
Uniprot IDs B2RAH5 O14974 Q13976
PDB IDs 2KJY 5HUZ 1ZXA 3NMD 3OCP 3OD0 3OGJ 4KU7 4KU8 4QX5 4QXK 4R4L 4R4M 4Z07 5J48 5JAX 5JD7 5L0N 6BDL 6BG2 6C0T
Enriched GO Terms of Interacting Partners?
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