TRIM37 and RPL9

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIM37	RPL9
Description		tripartite motif containing 37	ribosomal protein L9
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GO Annotations	Cellular Component	Cytoplasm Peroxisome Cytosol Aggresome ESC/E(Z) Complex Perinuclear Region Of Cytoplasm	Nucleus Cytosol Ribosome Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit
	Molecular Function	Chromatin Binding Ubiquitin-protein Transferase Activity Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of NF-kappaB Transcription Factor Activity Histone H2A Monoubiquitination Histone H2A-K119 Monoubiquitination Negative Regulation Of Centriole Replication Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Autoubiquitination Aggresome Assembly	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Cognitive function ( 25644384) General cognitive ability ( 29844566) Testicular germ cell tumor ( 23666239)	Alcohol consumption (drinks per week) ( 30643258)
Interacting Genes		63 interacting genes: ANKRD11 APEX2 APTX ARNT2 AXIN1 BYSL CCDC33 CDC20B CDK5RAP2 COPB1 CWF19L2 DDX6 DLGAP5 ELOA2 EWSR1 FAM107A FAM124B FAM161A FAM50B FXR2 H2AC20 H2AC4 IKBKG KAT5 KIAA0408 KIF9 LTBR MAGEB18 MCM10 MCRS1 NGFR NUDT18 PBK PNKP PRC1 RASD1 RHPN1 RIBC2 RNF6 RPL9 RXRB SCNM1 TNFRSF1B TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 UBASH3A UBB UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2U ZMAT2 ZNF329 ZNF417 ZNF655	22 interacting genes: CALCOCO2 CBY2 CCDC184 CEP76 DHPS ESR1 FAM9B HMBOX1 HOMEZ KXD1 MOCS2 MTUS2 PNMA2 RPS3 SORBS2 TIFA TRIM37 UBALD1 VCP ZBTB14 ZBTB7B ZBTB8A
Entrez ID		4591	6133
HPRD ID		05463	04732
Ensembl ID		ENSG00000108395	ENSG00000163682
Uniprot IDs		O94972	P32969 Q53Z07
PDB IDs		3LRQ	2CQL 4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
Enriched GO Terms of Interacting Partners?
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