MSH4 and EIF3F

Number of citations of the paper that reports this interaction (PubMedID 23725059)
5

Data Source:
BioGRID (pull down)

		MSH4	EIF3F
Description		mutS homolog 4	eukaryotic translation initiation factor 3 subunit F
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Synaptonemal Complex Nucleus Recombination Nodule	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Eukaryotic Translation Initiation Factor 3 Complex, EIF3m
	Molecular Function	DNA Binding Protein Binding DNA-dependent ATPase Activity Mismatched DNA Binding	Translation Initiation Factor Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Translation Initiation Factor Binding
	Biological Process	Resolution Of Meiotic Recombination Intermediates Ovarian Follicle Development Mismatch Repair Synapsis Reciprocal Meiotic Recombination Spermatogenesis Female Gamete Generation	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Protein Deubiquitination IRES-dependent Viral Translational Initiation
Pathways		Meiotic recombination	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs			Quercetin
Diseases
GWAS		Attention function in attention deficit hyperactive disorder ( 26174813) Daytime sleep phenotypes ( 27126917) Serum metabolite levels ( 23093944)	Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Depression (quantitative trait) ( 20800221)
Interacting Genes		9 interacting genes: ACADM DMC1 EIF3F MLH1 MLH3 MSH5 RAD51 RPA1 VBP1	19 interacting genes: APP ATXN1 CDK11A CDK11B CDK19 DKC1 EEF1A1 EIF3M FBXO32 HAX1 HNRNPK HTR2A MCPH1 MSH4 MTOR PTN RPS6KB1 SHBG SMAD9
Entrez ID		4438	8665
HPRD ID		03658	04887
Ensembl ID		ENSG00000057468	ENSG00000175390
Uniprot IDs		O15457	O00303
PDB IDs			3J8B 3J8C
Enriched GO Terms of Interacting Partners?
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