KRTAP5-6 and NLK

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KRTAP5-6	NLK
Description		keratin associated protein 5-6	nemo like kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Activity Protein Binding ATP Binding Transcription Factor Binding Ubiquitin Protein Ligase Binding SH2 Domain Binding
	Biological Process	Keratinization	MAPK Cascade Regulation Of Transcription, DNA-templated Protein Phosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway Wnt Signaling Pathway, Calcium Modulating Pathway Regulation Of Gene Expression Peptidyl-threonine Phosphorylation Negative Regulation Of Wnt Signaling Pathway Intracellular Signal Transduction Serine Phosphorylation Of STAT Protein Protein Autophosphorylation Protein Stabilization
Pathways		Keratinization	Ca2+ pathway
Drugs
Diseases
GWAS		Logical memory (delayed recall) in mild cognitive impairment ( 29274321)	Non-response to bupropion and depression ( 27622933)
Interacting Genes		26 interacting genes: ADAMTSL4 CATSPER1 CREB5 GLRX3 HOXA1 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP26-1 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 MEOX2 NLK NOTCH2NLA NUFIP2 OTX1 PLSCR1 RGS20 SMCP SPRY2	23 interacting genes: ASGR1 ATXN1 CREBBP CUL1 FBXW5 FOXO4 FOXP3 GRN HIPK2 KRTAP10-3 KRTAP4-2 KRTAP5-6 KRTAP5-9 LEF1 MYB MYBL1 QRICH1 RCHY1 SDR16C5 SKP2 STAT3 USP4 ZHX3
Entrez ID		440023	51701
HPRD ID		17250	17637
Ensembl ID		ENSG00000205864	ENSG00000087095
Uniprot IDs		Q6L8G9	A0A024QZ12 Q9UBE8
PDB IDs
Enriched GO Terms of Interacting Partners?
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