ASGR2 and CERS2

Number of citations of the paper that reports this interaction (PubMedID 11543633)
12

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		ASGR2	CERS2
Description		asialoglycoprotein receptor 2	ceramide synthase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Endoplasmic Reticulum Quality Control Compartment Perinuclear Region Of Cytoplasm	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding	DNA Binding Protein Binding N-acyltransferase Activity Sphingosine N-acyltransferase Activity
	Biological Process	Endocytosis Cell Surface Receptor Signaling Pathway Viral Process Protein N-linked Glycosylation Via Asparagine Bone Mineralization Regulation Of Protein Stability Lipid Homeostasis	Sphingolipid Biosynthetic Process Ceramide Biosynthetic Process Negative Regulation Of Axon Regeneration Negative Regulation Of Schwann Cell Migration Negative Regulation Of Schwann Cell Proliferation Involved In Axon Regeneration
Pathways		Asparagine N-linked glycosylation	Sphingolipid de novo biosynthesis
Drugs		Antihemophilic factor, human recombinant
Diseases
GWAS		Blood protein levels ( 29875488) Congenital heart disease (maternal effect) ( 28468790) Total cholesterol levels ( 30275531)	Body mass index ( 26426971) Estimated glomerular filtration rate ( 31152163 31015462) Facial attractiveness (female raters) ( 30946739) Glycated hemoglobin levels ( 28898252) HDL cholesterol ( 30275531) LDL cholesterol ( 24097068) LDL cholesterol levels ( 28334899) Reticulocyte fraction of red cells ( 27863252) Rhegmatogenous retinal detachment ( 23585552)
Interacting Genes		8 interacting genes: ASGR1 CERS2 F8 GLP1R GLUD1 HES1 MROH5 VKORC1	9 interacting genes: ASGR1 ASGR2 ATP6V0C HSP90AA1 PEX6 SLC19A2 SLC22A1 SLC39A1 TMBIM6
Entrez ID		433	29956
HPRD ID		00152	06080
Ensembl ID		ENSG00000161944	ENSG00000143418
Uniprot IDs		P07307 Q7Z4G9	Q96G23
PDB IDs
Enriched GO Terms of Interacting Partners?
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