MIA2 and CEP57

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MIA2	CEP57
Description		MIA SH3 domain ER export factor 2	centrosomal protein 57
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Endoplasmic Reticulum Exit Site	Nucleus Golgi Apparatus Centrosome Cytosol Microtubule
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding Fibroblast Growth Factor Binding Protein Homodimerization Activity Gamma-tubulin Binding
	Biological Process	ER To Golgi Vesicle-mediated Transport Protein Secretion Cargo Loading Into Vesicle	G2/M Transition Of Mitotic Cell Cycle Spermatid Development Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Microtubule Anchoring Protein Homooligomerization Ciliary Basal Body-plasma Membrane Docking
Pathways		Cargo concentration in the ER	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS			Cognitive ability (MTAG) ( 29186694) Erosive tooth wear (severe vs non-severe) ( 29898447) Feeling worry ( 29500382) Intelligence (MTAG) ( 29326435) Rheumatoid arthritis ( 30423114 24390342) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		13 interacting genes: CCHCR1 CEP57 DGCR6 EMILIN1 GRB2 MAGEB18 PSMA3 RASAL2 SEC23A SEC24C SS18L1 TLE5 TTC23L	14 interacting genes: APP FGF2 GCC1 KRT13 KRT15 KRT31 KRT40 MAGEA2B MEGF10 MIA2 MYC RALBP1 TFIP11 UIMC1
Entrez ID		4253	9702
HPRD ID		03680	16261
Ensembl ID		ENSG00000150527	ENSG00000166037
Uniprot IDs		Q4G155 Q59FD2 Q96PC5	Q86XR8
PDB IDs			4L0R
Enriched GO Terms of Interacting Partners?
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