MAP3K3 and MAP3K7

  • Number of citations of the paper that reports this interaction (PubMedID 16260783)
  • 37
  • Data Source:
  • HPRD (in vivo, two hybrid)

MAP3K3

MAP3K7

Description mitogen-activated protein kinase kinase kinase 3 mitogen-activated protein kinase kinase kinase 7
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Asthma ( 29273806)
  • Asthma (adult onset) ( 31036433)
  • Asthma (childhood onset) ( 31036433)
  • Bone mineral density (hip) ( 30172743)
  • Celiac disease ( 20190752)
  • Graves' disease ( 21841780)
  • Response to anti-TNF therapy in rheumatoid arthritis ( 26776603)
  • Response to inhaled corticosteroid treatment in asthma (change in FEV1) ( 24792382)
  • Severity of nausea and vomiting of pregnancy ( 29563502)
Interacting Genes 42 interacting genes: BIRC2 BRCA1 CDC37 COPS5 EGFR GAB1 GLRX3 GTF2I HSP90AA1 HSP90AB1 HSPA2 IKBKB MAP2K3 MAP2K4 MAP2K5 MAP2K7 MAP3K5 MAP3K7 MARK2 MBP NEDD4 NEDD4L NFKBIA PFDN2 PRKACA RCAN1 RIPK1 SMURF1 SPAG9 TOM1L1 TRAF6 TRAF7 VWF WNK1 XIAP YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ ZBTB16 65 interacting genes: BBS10 BCL10 CARD11 CHUK COPS5 CYLD EIF2AK2 ELP1 EZH2 FOS GPR25 HGS HIPK2 IKBKB IKBKG IL17RD IRAK1 MAP2K4 MAP2K6 MAP3K14 MAP3K3 MAP3K5 MAP4K1 MAP4K4 MAPK14 MAPK6 MAPK8 MAPK8IP1 MAVS MUL1 NAIP NDUFS6 NFKBIA NOD2 NRIP1 PEBP1 PELI3 PINK1 PPM1B PPM1L PPP2R1A PPP5C PRKAB1 RBX1 RELA RNF19A ROR2 SMAD3 SMAD6 SMAD7 STAT3 STRADB TAB1 TAB2 TGFBR1 TNFRSF11A TRAF3 TRAF3IP2 TRAF6 UBASH3A UBC VRK2 XIAP ZNF593 ZNF746
Entrez ID 4215 6885
HPRD ID 03965 04011
Ensembl ID ENSG00000198909 ENSG00000135341
Uniprot IDs J3KRN4 Q96HN9 Q99759 O43318
PDB IDs 2C60 2JRH 2O2V 2PPH 4Y5O 4YL6 2EVA 2YIY 4GS6 4L3P 4L52 4L53 4O91 5E7R 5GJD 5GJF 5GJG 5J7S 5J8I 5J9L 5JGA 5JGB 5JGD 5JH6 5JK3 5V5N
Enriched GO Terms of Interacting Partners?
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