MBD1 and CHAF1A

Number of citations of the paper that reports this interaction (PubMedID 17066076)
30

Data Source:
HPRD (two hybrid, in vivo)

		MBD1	CHAF1A
Description		methyl-CpG binding domain protein 1	chromatin assembly factor 1 subunit A
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck	Nuclear Chromatin Nucleus Protein-containing Complex CAF-1 Complex
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Methyl-CpG Binding Double-stranded Methylated DNA Binding Unmethylated CpG Binding	Chromatin Binding Protein Binding Identical Protein Binding Unfolded Protein Binding Chromo Shadow Domain Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Methylation-dependent Chromatin Silencing Transcription By RNA Polymerase II Heart Development Aging Neuron Differentiation Response To Nutrient Levels Response To Estradiol Response To Cocaine Regulation Of DNA Methylation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Astrocyte Differentiation	DNA Replication DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly Cell Cycle Chromatin Assembly
Pathways		SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 28165464)	Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Red cell distribution width ( 27863252 28957414)
Interacting Genes		25 interacting genes: APP ATF7IP ATF7IP2 ATXN1L CBX4 CBX5 CHAF1A ECT2 HDAC3 HIPK3 HTT OASL PIAS1 PIAS2 RNF2 SETDB1 SMAD1 SMAD3 SMAD5 SMAD7 SMAD9 SP1 SUV39H1 TENM1 ZNF512B	39 interacting genes: ANP32A ANP32B ASF1A ASF1B BLM CBX1 CBX5 CDC7 CDK2 CHAF1B CREBBP DBF4 DDX41 H3-4 H3C6 HMGB2 LZTR1 MBD1 MSH6 PABPC1 PCBD2 PCNA RBFOX2 REL SET SPOP SUMO1 SUMO2 SUMO3 TCERG1 TCF4 TRIM28 XRCC5 XRCC6 YWHAB YWHAE YWHAG YWHAQ ZNF408
Entrez ID		4152	10036
HPRD ID		01133	03148
Ensembl ID		ENSG00000141644	ENSG00000167670
Uniprot IDs		A8K654 B4DI41 B4DUR3 Q9UIS9	Q13111
PDB IDs		1D9N 1IG4 4D4W 5W9Q 6D1T
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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