MAN2A2 and GIT1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MAN2A2	GIT1
Description		mannosidase alpha class 2A member 2	GIT ArfGAP 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Integral Component Of Membrane	Mitochondrion Cytosol Focal Adhesion Membrane Calyx Of Held
	Molecular Function	Alpha-mannosidase Activity Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase Activity Hydrolase Activity, Hydrolyzing N-glycosyl Compounds Carbohydrate Binding Metal Ion Binding	GTPase Activator Activity Protein Binding Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Mannose Metabolic Process Protein Glycosylation N-glycan Processing Protein Deglycosylation	Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Cytokinesis Positive Regulation Of GTPase Activity Ephrin Receptor Signaling Pathway Presynaptic Modulation Of Chemical Synaptic Transmission Regulation Of Synaptic Vesicle Exocytosis
Pathways		Intra-Golgi traffic Reactions specific to the complex N-glycan synthesis pathway	Ephrin signaling Ephrin signaling Activation of RAC1 downstream of NMDARs
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057) Schizophrenia ( 25056061 29483656)
Interacting Genes		5 interacting genes: CHD3 ELP1 GIT1 LUC7L2 VIM	52 interacting genes: ARHGEF6 ARHGEF7 BARD1 C8orf33 CCDC113 CENPU CEP126 CHD3 DDX24 EIF6 ENTR1 GIT2 GPAA1 GRB2 GRK2 GRK3 GRK5 GRK6 HAP1 HMOX2 HTT KIF1A LAMTOR5 LPXN LRIF1 MAN2A2 NEK2 PAK3 PCLO PDPK1 PFDN1 PLCG1 PMF1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 PTK2 PTPRZ1 PXN RAN RGS2 RIF1 SRC SRRT TAB1 TERF1 TGFB1I1 TRIB3 TXNDC9 WDR33 YWHAG
Entrez ID		4122	28964
HPRD ID		02994	06577
Ensembl ID		ENSG00000196547	ENSG00000108262
Uniprot IDs		P49641	Q59FC3 Q9Y2X7
PDB IDs
Enriched GO Terms of Interacting Partners?
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