MAF and USF2

Number of citations of the paper that reports this interaction (PubMedID 9070273)
4

Data Source:
HPRD (in vitro, in vivo)

		MAF	USF2
Description		MAF bZIP transcription factor	upstream transcription factor 2, c-fos interacting
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nuclear Chromatin Nucleus Cytoplasm	Nuclear Chromatin Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Protein Homodimerization Activity BHLH Transcription Factor Binding Sequence-specific DNA Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cytokine Production Transcription By RNA Polymerase II Regulation Of Chondrocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cell Development Inner Ear Development Lens Fiber Cell Differentiation	Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Transcription By RNA Polymerase II Lactation Late Viral Transcription Positive Regulation Of Transcription By RNA Polymerase II Lipid Homeostasis
Pathways		RUNX2 regulates osteoblast differentiation	Estrogen-dependent gene expression
Drugs
Diseases		Multiple myeloma
GWAS		Alzheimer's disease (late onset) ( 30820047) Colorectal cancer ( 30529582) Depressive symptoms (SSRI exposure interaction) ( 25649181) Estimated glomerular filtration rate ( 31015462) Height ( 20668459) Lysophosphatidylcholine levels ( 31551469) Macular thickness ( 30535121) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244 24076602 21833088) Obesity ( 19151714) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Renal function-related traits (urea) ( 22797727) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Serum alkaline phosphatase levels ( 29403010) Serum thyroid-stimulating hormone levels ( 24852370) Serum uric acid levels ( 30993211) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Thyroid function ( 22494929) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 25743335) Thyroid volume ( 21565293) Urate levels ( 23263486)	Adverse response to drug ( 30420678) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Red cell distribution width ( 27863252 28957414)
Interacting Genes		17 interacting genes: ATF4 CREBBP EP300 ETS1 FOS FOSL1 HOXD12 JUN MAFA MAFB MAFG MYB NEU1 SMARCA5 SOX9 UBE2O USF2	10 interacting genes: BRCA1 EP300 FOS LZTS2 MAF NFYA PPARGC1A RELA TEAD2 USF1
Entrez ID		4094	7392
HPRD ID		01518	02668
Ensembl ID		ENSG00000178573	ENSG00000105698
Uniprot IDs		H3BP11 O75444	Q15853
PDB IDs
Enriched GO Terms of Interacting Partners?
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