LRP4 and WHRN

Number of citations of the paper that reports this interaction (PubMedID 12421765)
39

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LRP4	WHRN
Description		LDL receptor related protein 4	whirlin
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Postsynaptic Density Integral Component Of Membrane Dendrite Neuromuscular Junction Neuronal Cell Body Plasma Membrane Raft Synaptic Membrane	Photoreceptor Inner Segment Stereocilia Ankle Link Stereocilia Ankle Link Complex Cytoplasm Actin Filament Plasma Membrane Cell Junction Growth Cone Photoreceptor Connecting Cilium Stereocilium Stereocilium Tip Ciliary Basal Body Neuronal Cell Body Synapse Periciliary Membrane Compartment USH2 Complex
	Molecular Function	Calcium Ion Binding Protein Binding Receptor Tyrosine Kinase Binding Apolipoprotein Binding Protein Homodimerization Activity Scaffold Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Kidney Development Hair Follicle Development Endocytosis Dorsal/ventral Pattern Formation Proximal/distal Pattern Formation Wnt Signaling Pathway Negative Regulation Of Ossification Odontogenesis Of Dentin-containing Tooth Embryonic Digit Morphogenesis Dendrite Morphogenesis Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Axonogenesis Synapse Organization Synaptic Growth At Neuromuscular Junction Limb Development Skeletal Muscle Acetylcholine-gated Channel Clustering Negative Regulation Of Canonical Wnt Signaling Pathway Postsynaptic Membrane Assembly Presynaptic Membrane Assembly Amyloid-beta Clearance By Cellular Catabolic Process Positive Regulation Of Presynaptic Membrane Organization Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering	Retina Homeostasis Sensory Perception Of Sound Positive Regulation Of Gene Expression Cerebellar Purkinje Cell Layer Formation Establishment Of Protein Localization Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Sensory Perception Of Light Stimulus Auditory Receptor Cell Stereocilium Organization Inner Ear Receptor Cell Development Inner Ear Receptor Cell Stereocilium Organization Paranodal Junction Maintenance
Pathways		ECM proteoglycans
Drugs
Diseases		Cenani-Lenz syndactyly syndrome	Usher syndrome (US) Deafness, autosomal recessive
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Bone mineral density (hip) ( 19079262) D-dimer levels ( 21502573) General risk tolerance (MTAG) ( 30643258) HDL cholesterol ( 24097068 20686565) HDL cholesterol levels ( 28334899) Heel bone mineral density ( 30598549 28869591) Intraocular pressure ( 29617998) Mood instability ( 31168069) Pre-treatment viral load in HIV-1 infection ( 31219150) Reaction time ( 29844566) Systolic blood pressure ( 30224653) Urate levels ( 31578528) Venous thromboembolism ( 31420334)
Interacting Genes		1 interacting genes: WHRN	6 interacting genes: CASK LRP4 LRRC4C MYO15A MYO7A RPS6KA1
Entrez ID		4038	25861
HPRD ID		18517	09718
Ensembl ID		ENSG00000134569	ENSG00000095397
Uniprot IDs		O75096	B9EGE6 Q9P202
PDB IDs			1UEZ 1UF1 1UFX
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?