LMO2 and TFPT

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		LMO2	TFPT
Description		LIM domain only 2	TCF3 fusion partner
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Factor Complex	Nucleus Nucleoplasm Cytoplasm Ino80 Complex Nuclear Membrane
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding BHLH Transcription Factor Binding Metal Ion Binding Cofactor Binding E-box Binding	DNA Binding Protein Binding
	Biological Process	Multicellular Organism Development MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Thyroid Hormone Stimulus Regulation Of Hematopoietic Stem Cell Differentiation	DNA Repair DNA Recombination Protein Deubiquitination Positive Regulation Of Apoptotic Process Apoptotic Signaling Pathway
Pathways		RUNX1 regulates transcription of genes involved in differentiation of HSCs	UCH proteinases DNA Damage Recognition in GG-NER
Drugs
Diseases		Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Cognitive performance ( 19734545) Iron status biomarkers (transferrin saturation) ( 28334935) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Red blood cell count ( 27863252)	Obesity-related traits ( 23251661)
Interacting Genes		97 interacting genes: ABI2 ADAMTSL4 AFDN AGTRAP AIMP2 ALDH6A1 AXIN1 BANP BEX2 BLZF1 C1orf94 CALCOCO2 CBY2 CCDC33 CDC25A CDC5L CDX4 CLHC1 CMTM5 CORO1A CORO1C DAZAP2 DBF4B DDIT3 DRAP1 EHMT2 ELF2 ERBIN FHL3 GATA1 GATA2 GATA3 GFAP GOLGA2 GRB2 HNRNPC HNRNPM HOOK1 IFT43 IHO1 IKZF3 ISL1 KANK2 KDM5A KIF3B KRT15 KRT40 KRTAP10-7 LDB1 LYL1 LZTS2 MAGEA8 MAPRE1 MAPRE2 MAPRE3 MBIP MRFAP1L1 MTUS2 N4BP2L2 NCAPH2 NHLH1 NIF3L1 NOTCH2NLA NUP62 NUTM1 PDE9A PHC2 PRKG1 RBBP8 REL RELA RINT1 RLIM ROCK1 SAXO1 SKP1 SMAD2 SOX5 SP1 SSX2IP STAT1 STAT3 STIP1 TAL1 TAL2 TFPT TLE5 TLX3 TRIM23 TRIM54 TRIP6 TSC22D4 TUFT1 UBA6 UBE2I ZFP64 ZNF24	27 interacting genes: APP C4orf46 CCNDBP1 CDCA7L CNN1 DDIT4L DEUP1 DYDC1 EAF1 EAF2 ELL ENTR1 HAUS1 KRT19 LMO2 NOL3 PAWR PIM1 RALBP1 RPGRIP1 RUNDC3A STK3 TCF3 TFIP11 TPM1 TPM3 TRAF1
Entrez ID		4005	29844
HPRD ID		01586	10266
Ensembl ID		ENSG00000135363	ENSG00000105619
Uniprot IDs		P25791	A0A024R4Q5 P0C1Z6
PDB IDs		2XJY 2XJZ 2YPA 4KFZ
Enriched GO Terms of Interacting Partners?
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