LIMK2 and ROCK1

  • Number of citations of the paper that reports this interaction (PubMedID 11018042)
  • 87
  • Data Source:
  • HPRD (in vitro, in vivo)

LIMK2

ROCK1

Description LIM domain kinase 2 Rho associated coiled-coil containing protein kinase 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Eosinophil counts ( 27863252)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Eosinophil percentage of white cells ( 27863252)
  • Multiple sclerosis ( 31604244)
  • Neutrophil percentage of granulocytes ( 27863252)
  • Paclitaxel-induced neuropathy ( 23776197)
  • Sum eosinophil basophil counts ( 27863252)
  • Type 2 diabetes nephropathy ( 21150874)
  • Asthma exacerbations in inhaled corticosteroid treatment ( 30697902)
  • Lysophosphatidylcholine levels ( 31551469)
  • Telomere length ( 30185882)
Interacting Genes 12 interacting genes: CDC42BPA CFL1 FBXO7 GSN H1-1 HIPK3 LIMK1 MBP NF1 PARD3 ROCK1 RPS6KA1 35 interacting genes: ADD1 ARHGAP24 CASP3 CASP7 CDC25A CDC34 CFAP206 CRMP1 DES DPYSL2 EZR FAM124A GFAP IKBKB IRS1 ITSN2 LIMK1 LIMK2 LMO2 MAGEB4 MLC1 MSN PFN2 POLR3C PPP1R12A PTK2 RDX RHOA RHOC RND3 SMAD2 TRIM15 TSG101 UBE2T VIM
Entrez ID 3985 6093
HPRD ID 03585 03414
Ensembl ID ENSG00000182541 ENSG00000067900
Uniprot IDs A0A024R1H6 A0A024R1M2 P53671 Q13464
PDB IDs 1X6A 4TPT 5NXD 1S1C 2ESM 2ETK 2ETR 2V55 3D9V 3NCZ 3NDM 3O0Z 3TV7 3TWJ 3V8S 4L2W 4W7P 4YVC 4YVE 5BML 5F5P 5HVU 5KKS 5KKT 5UZJ 5WNE 5WNF 5WNG 5WNH 6E9W
Enriched GO Terms of Interacting Partners?
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