LAMA4 and BRD7

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LAMA4	BRD7
Description		laminin subunit alpha 4	bromodomain containing 7
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Collagen-containing Extracellular Matrix Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Signaling Receptor Binding Extracellular Matrix Structural Constituent Protein Binding	P53 Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Histone Binding Transcription Regulatory Region DNA Binding Lysine-acetylated Histone Binding
	Biological Process	Cell Adhesion Regulation Of Cell Adhesion Extracellular Matrix Organization Regulation Of Cell Migration Regulation Of Embryonic Development Negative Regulation Of Cold-induced Thermogenesis	Regulation Of Transcription By RNA Polymerase II Cell Cycle Negative Regulation Of Cell Proliferation Wnt Signaling Pathway Positive Regulation Of Histone Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans MET activates PTK2 signaling	Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Metabolite levels ( 23823483)	Allergic sensitization ( 30013184) Epilepsy ( 30531953) Liver enzyme levels (alanine transaminase) ( 24124411) Medication use (thyroid preparations) ( 31015401)
Interacting Genes		16 interacting genes: APC ATF7IP BRD7 COPS6 EEF1A1 GAPDH HDAC2 LRIF1 MED31 PTN RTN4 TP53 TUBB2A UBR1 UNC119 ZHX1	30 interacting genes: AGR2 BARD1 BHLHE40 BRD3 BTBD2 DVL1 FTH1 H2AC16 H2BC21 H3-3A H3-4 H3C14 H4-16 HAP1 HNRNPUL1 IRF2 LAMA4 LRIF1 MX1 NEFL PAFAH1B3 PCBD1 PSMD11 PTPN13 RBFOX2 RIF1 RPLP1 SERPINB9 TP53 TRIM24
Entrez ID		3910	29117
HPRD ID		02532	12531
Ensembl ID		ENSG00000112769	ENSG00000166164
Uniprot IDs		A0A0A0MQS9 A0A0A0MTC7 Q16363 Q5D044	Q9NPI1
PDB IDs			2I7K 5MQ1
Enriched GO Terms of Interacting Partners?
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