INSC and GPSM1

Number of citations of the paper that reports this interaction (PubMedID 16458856)
9

Data Source:
HPRD (in vivo)

		INSC	GPSM1
Description		INSC spindle orientation adaptor protein	G protein signaling modulator 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Cortex Protein-containing Complex	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Cell Cortex Protein-containing Complex
	Molecular Function	Protein Binding Protein Domain Specific Binding Protein Binding, Bridging	GDP-dissociation Inhibitor Activity Protein Binding
	Biological Process	Nervous System Development Asymmetric Cell Division Cell Differentiation Regulation Of Protein Stability	Nervous System Development Positive Regulation Of Macroautophagy Cell Differentiation Negative Regulation Of GTPase Activity Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity
Pathways			G alpha (i) signalling events
Drugs
Diseases
GWAS		Expressive vocabulary in infants ( 25226531) Heel bone mineral density ( 30598549 28869591) Menarche (age at onset) ( 23667675) Obesity-related traits ( 23251661)	Acute insulin response (insulin secretion adjusted) ( 28490609) Birth weight ( 31043758) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Insulinogenic index ( 23263489) Joint damage in rheumatoid arthritis ( 26498133) Offspring birth weight ( 31043758) Type 2 diabetes ( 30297969 29632382 26818947 23945395 31118516 30718926 28869590) Type 2 diabetes (adjusted for BMI) ( 29632382) Ulcerative colitis ( 28067908) White blood cell count ( 29403010)
Interacting Genes		5 interacting genes: GPSM1 GPSM2 LNX1 PARD3 PARD3B	12 interacting genes: CCDC158 DAZAP2 GNAI1 GNAI3 INSC KANK2 MAP1LC3A OSTM1 TRIP13 USHBP1 USP9X ZBED1
Entrez ID		387755	26086
HPRD ID		18803	17075
Ensembl ID		ENSG00000188487	ENSG00000160360
Uniprot IDs		Q1MX18	A0A087WVF5 A0A0A0MRC4 A0A0A0MSK4 Q86YR5
PDB IDs		3SF4
Enriched GO Terms of Interacting Partners?
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