KRTAP12-4 and HMGB4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KRTAP12-4	HMGB4
Description		keratin associated protein 12-4	high mobility group box 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Nuclear Chromatin Nucleus Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Transcription Factor Binding DNA Binding, Bending
	Biological Process	Keratinization	Activation Of Innate Immune Response DNA Recombination Chromatin Remodeling Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Regulation Of Signaling Receptor Activity Positive Regulation Of Autophagy Developmental Process Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Innate Immune Response Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Interleukin-1 Secretion Positive Regulation Of Interleukin-1 Beta Secretion Cell Chemotaxis Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Interferon-alpha Secretion
Pathways		Keratinization
Drugs
Diseases
GWAS			Depressive symptoms (SSRI exposure interaction) ( 25649181)
Interacting Genes		9 interacting genes: ARID5A HMGB4 HOXA1 IQUB MEOX2 NOTCH2NLA OTX1 PIH1D2 VENTX	3 interacting genes: APP CEP70 KRTAP12-4
Entrez ID		386684	127540
HPRD ID		11200	14038
Ensembl ID		ENSG00000212933	ENSG00000176256
Uniprot IDs		P60329	Q8WW32
PDB IDs
Enriched GO Terms of Interacting Partners?
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