KRTAP10-9 and NPPB

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KRTAP10-9	NPPB
Description		keratin associated protein 10-9	natriuretic peptide B
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Extracellular Region Extracellular Space Nucleus Cytoplasm Protein-containing Complex
	Molecular Function	Protein Binding	Signaling Receptor Binding Hormone Activity Protein Binding Diuretic Hormone Activity Hormone Receptor Binding
	Biological Process	Keratinization	Negative Regulation Of Systemic Arterial Blood Pressure CGMP Biosynthetic Process Protein Folding Cell Surface Receptor Signaling Pathway Receptor Guanylyl Cyclase Signaling Pathway Neuropeptide Signaling Pathway Body Fluid Secretion Regulation Of Blood Pressure Negative Regulation Of Angiogenesis CGMP-mediated Signaling Negative Regulation Of Cell Growth Positive Regulation Of Urine Volume Positive Regulation Of Renal Sodium Excretion Regulation Of Vascular Permeability Regulation Of Blood Vessel Diameter
Pathways		Keratinization
Drugs			Carvedilol Oxymetholone
Diseases
GWAS			B-type natriuretic peptide levels ( 29237677 25561047) B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio ( 29237677) Blood pressure ( 21909110) Blood protein levels ( 30072576 29875488) Blood protein levels in cardiovascular risk ( 28369058) Diastolic blood pressure ( 28739976 27618452) Diastolic blood pressure (cigarette smoking interaction) ( 29455858) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) N-terminal pro B-type natriuretic peptide levels ( 29237677) NT-proBNP levels in acute coronary syndrome ( 26908625) Pulse pressure ( 30578418) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure ( 19430483 28739976 27618447 27618452) Systolic blood pressure (cigarette smoking interaction) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Tuberculosis ( 29036319)
Interacting Genes		165 interacting genes: ADAMTSL4 ALDH3B1 ALPI ARFGAP1 ATXN7L1 AVPI1 BCL6B C10orf62 C11orf87 C19orf57 C5orf60 CATIP CATSPER1 CBX2 CCDC26 CD300LG CDKL3 CHIC2 CHRD CHRNG CKS1B CLK4 CNNM3 CRCT1 CREB5 CST9L CXCL16 DHX57 DMRT3 DOCK2 EIF4E2 FAM124B FAM161A FAM74A4 FAM76B FARS2 GABARAPL1 GABARAPL2 GATA2 GLIDR GLP1R GLRX3 GNE GPATCH2L GSTP1 HBG1 HBZ HCK HOXA1 HOXB9 HPCAL1 HSD3B7 IGSF8 INPP5D IQUB ITGB5 KAT5 KIF9 KLHL38 KRT20 KRT83 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP12-1 KRTAP26-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE3C LCE3E LCE4A LUZP4 MAB21L3 MAPKBP1 MED30 MEOX2 MOBP MT1DP MXI1 NAXD NECTIN3 NOTCH2NLA NPBWR2 NPDC1 NPPB NR1D2 NUFIP2 OTX1 PGAP2 PGLS PIN1 PLSCR1 PRKAB2 PRPF31 PTGER3 PVR RAB7A RHNO1 RSPO2 SCARB1 SCNM1 SHFL SLC23A1 SLC6A20 SMARCE1 SMCP SPACA9 SPATA3 SPATA8 SPG7 SPRY1 SPRY2 STK16 TBC1D16 TBC1D23 TEDC2 TGOLN2 THAP10 TLE5 TNFRSF6B TNP2 TRIM41 TRIM42 TXNDC5 TYMSOS TYRO3 UTP23 WNT11 WT1 WT1-AS XCL2 ZBTB24 ZBTB38 ZBTB9 ZFYVE26 ZNF124 ZNF155 ZNF20 ZNF264 ZNF317 ZNF417 ZNF439 ZNF440 ZNF473 ZNF564 ZNF572 ZNF578 ZNF581 ZNF587 ZNF625 ZNF688 ZNF697 ZNF699 ZNF792 ZNF844 ZSCAN21 ZSCAN26	10 interacting genes: EWSR1 HDAC4 KRT40 KRTAP10-3 KRTAP10-9 NOTCH2NLA NPR1 NPR2 NPR3 PSMA3
Entrez ID		386676	4879
HPRD ID		11195	08974
Ensembl ID		ENSG00000221837	ENSG00000120937
Uniprot IDs		P60411	P16860
PDB IDs			1YK1 3N56
Enriched GO Terms of Interacting Partners?
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