KRT13 and CEP57

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KRT13	CEP57
Description		keratin 13	centrosomal protein 57
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome	Nucleus Golgi Apparatus Centrosome Cytosol Microtubule
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding Microtubule Binding Fibroblast Growth Factor Binding Protein Homodimerization Activity Gamma-tubulin Binding
	Biological Process	Cytoskeleton Organization Keratinization Cornification	G2/M Transition Of Mitotic Cell Cycle Spermatid Development Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Microtubule Anchoring Protein Homooligomerization Ciliary Basal Body-plasma Membrane Docking
Pathways		Keratinization Formation of the cornified envelope	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases		White sponge nevus
GWAS			Cognitive ability (MTAG) ( 29186694) Erosive tooth wear (severe vs non-severe) ( 29898447) Feeling worry ( 29500382) Intelligence (MTAG) ( 29326435) Rheumatoid arthritis ( 30423114 24390342) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		52 interacting genes: ABI2 ABI3 AMOTL2 ANKRD36BP1 APC ATP5PO BLOC1S6 C1orf109 C1orf216 C2CD6 CCHCR1 CCNC CEP57 CEP57L1 DNAAF4 EIF4E2 EXOSC5 FANCG FARS2 FBF1 GFAP GOLGA8EP GRAP2 HGS IFT20 KLC3 KLC4 KRT2 KRT20 KRT4 KRT6A KRT6B KRT6C KRT7 KRT71 KRT79 KRT8 LSM2 MOS MYH1 NEFL PPP1R18 PSMB1 PSMB2 RTL8B SGF29 TLE5 TMSB4X TRIM42 TSG101 TXLNA ZNF688	14 interacting genes: APP FGF2 GCC1 KRT13 KRT15 KRT31 KRT40 MAGEA2B MEGF10 MIA2 MYC RALBP1 TFIP11 UIMC1
Entrez ID		3860	9702
HPRD ID		01016	16261
Ensembl ID		ENSG00000171401	ENSG00000166037
Uniprot IDs		A1A4E9 P13646	Q86XR8
PDB IDs			4L0R
Enriched GO Terms of Interacting Partners?
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