KPNA3 and FTL

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KPNA3	FTL
Description		karyopherin subunit alpha 3	ferritin light chain
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Pore Nucleoplasm Cytosol Host Cell	Extracellular Region Cell Cytoplasm Cytosol Intracellular Ferritin Complex Membrane Azurophil Granule Lumen Autolysosome Extracellular Exosome
	Molecular Function	Protein Binding Protein C-terminus Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity	Iron Ion Binding Protein Binding Ferrous Iron Binding Ferric Iron Binding Identical Protein Binding
	Biological Process	NLS-bearing Protein Import Into Nucleus Modulation By Virus Of Host Process Viral Entry Into Host Cell Protein-containing Complex Assembly Viral Penetration Into Host Nucleus	Iron Ion Transport Cellular Iron Ion Homeostasis Intracellular Sequestering Of Iron Ion Neutrophil Degranulation Iron Ion Homeostasis
Pathways		ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways	Scavenging by Class A Receptors Golgi Associated Vesicle Biogenesis Neutrophil degranulation Iron uptake and transport
Drugs			Iron Dextran Protoporphyrin Sodium ferric gluconate complex
Diseases			Neurodegeneration with brain iron accumulation (NBIA); Hallervorden-Spatz syndrome; Neuroferritinopathy; Aceruloplasminemia
GWAS		Inflammatory skin disease ( 25574825) Menopause (age at onset) ( 22267201) Obesity-related traits ( 23251661) Triiodothyronine/thyroxine ratio ( 30824882)
Interacting Genes		33 interacting genes: APOL6 ARNT CDKN1B COIL DDX21 EPAS1 EPHA2 ERCC3 FAM50B FTL GATA6 GTF2H1 GTF2IRD1 HIF1A HNRNPC HSPB1 KPNB1 MAT2B MVP MYOD1 NFE2L2 NFKB1 NUP50 RBBP4 RCC1 RPRD1A SLC5A11 TEX37 TGM2 TSSC4 ZBTB24 ZCCHC10 ZNF131	26 interacting genes: CLEC4G FTH1 GADD45A GLP1R GRB2 HTT IGDCC3 KNG1 KPNA3 MAP3K12 MPHOSPH6 MPP6 MTNR1B MYOC MYOG PIK3CA PPP1CC PTN RAP2A SDCBP SMAD9 SPINK7 TAF10 USHBP1 VKORC1 ZDHHC17
Entrez ID		3839	2512
HPRD ID		03536	00616
Ensembl ID		ENSG00000102753	ENSG00000087086
Uniprot IDs		A0A024RDV7 O00505	A0A384MDR3 P02792
PDB IDs			2FFX 2FG4 2FG8 3KXU 4V6B 5LG8
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?