KIT and INPP5D

  • Number of citations of the paper that reports this interaction (PubMedID 11071635)
  • 24
  • Data Source:
  • HPRD (in vitro)

KIT

INPP5D

Description KIT proto-oncogene, receptor tyrosine kinase inositol polyphosphate-5-phosphatase D
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Alzheimer's disease (late onset) ( 30617256 24162737)
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Contrast sensitivity ( 24152035)
  • Crohn's disease ( 22412388 23128233)
  • Eosinophil counts ( 27863252)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Eosinophil percentage of white cells ( 27863252)
  • Family history of Alzheimer's disease ( 30617256)
  • Neutrophil percentage of granulocytes ( 27863252)
  • Perceived unattractiveness to mosquitoes ( 28199695)
  • Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
  • Sum eosinophil basophil counts ( 27863252)
Interacting Genes 60 interacting genes: ABL1 BTK CBL CBLB CD81 CD9 CISH CLTC CRK CRKL CSF1R CSF2RA CSF2RB DOK1 EPOR FYN GRAP GRAP2 GRB10 GRB2 GRB7 HCK IL7R ILKAP INPP5D JAK2 JAK3 KITLG LCK LYN MATK MPDZ PIK3CG PIK3R1 PIK3R2 PLCE1 PLCG1 PRKCA PRKCB PTPN11 PTPN20 PTPN6 PTPRO PTPRU RASA1 SH2B2 SH2B3 SOCS1 SOCS5 SOCS6 SPRED1 SPRED2 SRC STAP1 STAT1 STAT5A STAT5B STYX TEC YES1 42 interacting genes: ARAP1 CD22 CD300LF CRKL CSF1R CSF3R DAB1 DAB2 DOK1 DOK2 DOK3 EPOR FCGR1B FCGR2B FGR FLT3 GAB1 GAB2 GRB2 HCK IL4R JAK1 JAK3 KHDRBS3 KIT KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 LILRB4 LYN MET NOTCH2NLA PECAM1 PLCG1 PTPN11 SH3KBP1 SHC1 SLAMF1 XIAP ZDHHC17
Entrez ID 3815 3635
HPRD ID 01287 09033
Ensembl ID ENSG00000157404 ENSG00000168918
Uniprot IDs A0A0U2N547 P10721 Q92835
PDB IDs 1PKG 1QZJ 1QZK 1R01 1T45 1T46 2E9W 2EC8 2IUH 2VIF 3G0E 3G0F 4HVS 4K94 4K9E 4PGZ 4U0I 6GQJ 6GQK 6GQL 6GQM 6HH1 6ITT 6ITV 6KLA 6MOB 2YSX 6IBD
Enriched GO Terms of Interacting Partners?
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