KIF5C and KIF5A

Number of citations of the paper that reports this interaction (PubMedID 10964943)
88

Data Source:
HPRD (in vivo)

		KIF5C	KIF5A
Description		kinesin family member 5C	kinesin family member 5A
Image		No pdb structure
GO Annotations	Cellular Component	Cell Kinesin Complex Microtubule Dendrite Cytoplasm Ciliary Rootlet Neuronal Cell Body Axonal Growth Cone Distal Axon Axon Cytoplasm	Cell Cytosol Kinesin Complex Microtubule Membrane Dendrite Cytoplasm Ciliary Rootlet Perikaryon Synapse Perinuclear Region Of Cytoplasm Axon Cytoplasm
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity	Motor Activity Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Kinesin Binding
	Biological Process	Organelle Organization Microtubule-based Movement Axon Guidance Motor Neuron Axon Guidance Cytoskeleton-dependent Intracellular Transport Synaptic Vesicle Transport MRNA Transport Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex Anterograde Axonal Protein Transport	Retrograde Vesicle-mediated Transport, Golgi To ER Microtubule-based Movement Chemical Synaptic Transmission Axon Guidance Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cytoskeleton-dependent Intracellular Transport Synaptic Vesicle Transport Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex Anterograde Axonal Protein Transport Retrograde Neuronal Dense Core Vesicle Transport
Pathways		Insulin processing	MHC class II antigen presentation Insulin processing RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases			Hereditary spastic paraplegia (SPG)
GWAS		Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Chronotype ( 30696823)	Amyotrophic lateral sclerosis ( 29566793) Rheumatoid arthritis ( 24449572 18794853) Smoking initiation (ever regular vs never regular) ( 30679032)
Interacting Genes		7 interacting genes: CSNK2A1 KIF5A KLC1 KLC3 NCOA2 SNAPIN YWHAG	16 interacting genes: DTNB ITSN1 KCNE3 KIF5B KIF5C KLC3 MAP4K4 NCOA2 NDEL1 PIN1 RAPGEF2 SMN1 TK1 TP53BP2 TSG101 YAP1
Entrez ID		3800	3798
HPRD ID		18371	09108
Ensembl ID		ENSG00000168280	ENSG00000155980
Uniprot IDs		O60282 Q59GB8	Q12840
PDB IDs			4UXT 4UXY 4UY0
Enriched GO Terms of Interacting Partners?
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