STT3A and ITM2C

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		STT3A	ITM2C
Description		STT3 oligosaccharyltransferase complex catalytic subunit A	integral membrane protein 2C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Oligosaccharyltransferase Complex Membrane Integral Component Of Membrane Oligosaccharyltransferase III Complex	Lysosome Lysosomal Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding Metal Ion Binding	Amyloid-beta Binding Protein Binding ATP Binding
	Biological Process	Protein N-linked Glycosylation Via Asparagine Co-translational Protein Modification Post-translational Protein Modification	Negative Regulation Of Neuron Projection Development Neuron Differentiation Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Asparagine N-linked glycosylation
Drugs
Diseases
GWAS		Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Breast cancer (survival) ( 25890600) Schizophrenia ( 21926974)
Interacting Genes		6 interacting genes: CSDE1 HJURP IRAK2 ITM2C SARM1 STING1	5 interacting genes: BACE1 FURIN MTNR1B RNF7 STT3A
Entrez ID		3703	81618
HPRD ID		03086	17167
Ensembl ID		ENSG00000134910	ENSG00000135916
Uniprot IDs		P46977	B8ZZM6 Q9NQX7
PDB IDs
Enriched GO Terms of Interacting Partners?
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