ITGB5 and NUMB

  • Number of citations of the paper that reports this interaction (PubMedID 12606711)
  • 115
  • Data Source:
  • HPRD (in vitro)

ITGB5

NUMB

Description integrin subunit beta 5 NUMB endocytic adaptor protein
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Airway hyperresponsiveness ( 23984888)
  • Carpal tunnel syndrome ( 30833571)
  • Coronary artery disease ( 28714974)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Diastolic blood pressure ( 27841878)
  • Heel bone mineral density ( 30598549)
  • Pulse pressure ( 27841878)
  • Systolic blood pressure ( 27841878 30578418)
  • Bipolar disorder with mood-incongruent psychosis ( 23092984)
  • Coronary artery calcification ( 17903303)
  • Macular thickness ( 30535121)
  • Multisite chronic pain ( 31194737)
Interacting Genes 36 interacting genes: ANXA5 CCN1 DAB1 DAB2 DOK1 EHMT2 EPS8 EWSR1 FHL2 FLNA ITGA5 ITGAV ITGB3BP KRT40 KRTAP10-8 KRTAP10-9 LTBP1 LTBP3 MTDH MTUS2 MYO10 NOTCH2NLA NUMB P2RY2 PAK4 PALLD PPARD PTK2 RACK1 SNTA1 SPP1 SRSF9 STAB2 TLN1 TNS2 ZBTB17 33 interacting genes: AP2A1 AP2A2 APP DNAJC5 DPYSL2 EGFR EPS15 FBXO7 FRS3 IRS1 ITCH ITGB2 ITGB3 ITGB5 L1CAM LNX1 LNX2 MAPK8IP2 MDM2 NEDD4 NOTCH1 OLIG1 PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCZ PTEN RPL3 SIAH1 TERF2
Entrez ID 3693 8650
HPRD ID 00949 04767
Ensembl ID ENSG00000082781 ENSG00000133961
Uniprot IDs D3DNA1 L7RT22 P18084 A0A024R681 A0A024R684 A0A024R6C4 A0A024R6F4 P49757
PDB IDs 5NJJ 5NJK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?