INSR and SORBS1

  • Number of citations of the paper that reports this interaction (PubMedID 11374898)
  • 18
  • Data Source:
  • HPRD (in vitro, in vivo)

INSR

SORBS1

Description insulin receptor sorbin and SH3 domain containing 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Diabetic nephropathy in type 1 diabetes ( 25476525)
  • Estimated glomerular filtration rate ( 31152163)
  • Obesity-related traits ( 23251661)
  • PR interval ( 30046033)
  • Staphylococcus aureus nasal carriage (persistent) ( 26569114)
  • Suicide risk ( 21041247)
Interacting Genes 86 interacting genes: ACP1 ADRB2 AHSG ARF1 ARHGAP26 CALM1 CALM2 CALM3 CAV1 CAV3 CBL CCDC88A CEACAM1 CRK CRKL CSK DOK1 DOK4 DOK5 DUSP18 DUSP19 ENPP1 ERBB2 FABP4 FRS2 GAB1 GRB10 GRB14 GRB7 HRAS IGF1R IGF2 INS INSRR IRF7 IRS1 IRS2 JAK1 JAK2 KHDRBS1 KRT27 KRT31 MAD2L1 MAPK3 MARCHF1 PIK3R1 PIK3R3 PLCG1 PRKCA PRKCD PTK2 PTPN1 PTPN11 PTPN12 PTPN2 PTPN6 PTPRC PTPRF PTPRR RACK1 RAF1 RASA1 SH2B1 SH2B2 SHC1 SMAD2 SNX1 SNX2 SNX4 SNX6 SOCS1 SOCS2 SOCS3 SOCS6 SORBS1 SRC STAT5A STAT5B STUB1 STYX SYNCRIP TEAD1 TRIM72 VAV1 VAV3 YWHAB 25 interacting genes: ABL1 ACTA1 ADAM15 AFDN CBL CDK6 EFNB1 FLOT1 INPPL1 INSM1 INSR KHDRBS1 MAP4K3 PAK2 PGR PILRA PTK2 PXN RPL4 SEMA6A SH2B2 SLC10A3 SRC TENM1 VCL
Entrez ID 3643 10580
HPRD ID 00975 05587
Ensembl ID ENSG00000171105 ENSG00000095637
Uniprot IDs P06213 B4DTX5 Q9BX66
PDB IDs 1GAG 1I44 1IR3 1IRK 1P14 1RQQ 2AUH 2B4S 2HR7 2MFR 2Z8C 3BU3 3BU5 3BU6 3EKK 3EKN 3ETA 3W11 3W12 3W13 4IBM 4OGA 4XLV 4XSS 4XST 4ZXB 5E1S 5HHW 5J3H 5KQV 5U1M 6HN4 6HN5 6PXV 6PXW 6SOF 2DL3 2ECZ 2LJ0 2LJ1 2MOX 2O2W 2O31 2O9S 2O9V 4LN2 4LNP
Enriched GO Terms of Interacting Partners?
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