INPPL1 and HYOU1

		INPPL1	HYOU1
Description		inositol polyphosphate phosphatase like 1	hypoxia up-regulated 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Golgi Apparatus Cytosol Cytoskeleton Plasma Membrane Nuclear Speck Lamellipodium Filopodium	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen Smooth Endoplasmic Reticulum Focal Adhesion Membrane Endoplasmic Reticulum Chaperone Complex Extracellular Exosome Endocytic Vesicle Lumen
	Molecular Function	Actin Binding Protein Binding Hydrolase Activity SH3 Domain Binding SH2 Domain Binding	Protein Binding ATP Binding Chaperone Binding
	Biological Process	Endochondral Ossification Immune System Process Glucose Metabolic Process Phosphatidylinositol Biosynthetic Process Endocytosis Actin Filament Organization Cell Adhesion Negative Regulation Of Cell Proliferation Post-embryonic Development Negative Regulation Of Gene Expression Cytokine-mediated Signaling Pathway Response To Insulin Inositol Phosphate Metabolic Process Phosphatidylinositol Dephosphorylation Ruffle Assembly	Response To Ischemia ER To Golgi Vesicle-mediated Transport Receptor-mediated Endocytosis Response To Endoplasmic Reticulum Stress IRE1-mediated Unfolded Protein Response Cellular Response To Hypoxia Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Pathways		Synthesis of PIPs at the plasma membrane Synthesis of IP3 and IP4 in the cytosol Interleukin receptor SHC signaling	Scavenging by Class F Receptors Scavenging by Class F Receptors XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Heart rate response to recovery post exercise (10 sec) ( 29497042)	Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		17 interacting genes: ABL1 ARAP3 BCAR1 CBL CD4 CSF1R EGFR FCGR2B FLNC HID1 HYOU1 MET SHC1 SORBS1 SORBS3 SRC UBC	12 interacting genes: CADM1 DPYSL3 IL1R1 IL1RL1 INPPL1 NXPE4 PPP2R1B RBM7 SEL1L TAGLN TMEM245 TP53BP2
Entrez ID		3636	10525
HPRD ID		02900	03448
Ensembl ID		ENSG00000165458	ENSG00000149428
Uniprot IDs		O15357	A0A384P5T6 A0A494C039 B3KXH0 B7Z602 B7Z766 Q6IN67 Q9Y4L1
PDB IDs		2K4P 2KSO 2MK2 3NR8 4A9C 5OKM 5OKN 5OKO 5OKP
Enriched GO Terms of Interacting Partners?
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