APOH and GEM

Number of citations of the paper that reports this interaction (PubMedID 18624398)
14

Data Source:
BioGRID (two hybrid)

		APOH	GEM
Description		apolipoprotein H	GTP binding protein overexpressed in skeletal muscle
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Surface Platelet Dense Granule Lumen Very-low-density Lipoprotein Particle High-density Lipoprotein Particle Chylomicron Collagen-containing Extracellular Matrix Extracellular Exosome	Cell Nucleus Plasma Membrane Cytoplasmic Side Of Plasma Membrane Midbody Spindle Midzone Mitotic Spindle
	Molecular Function	Protein Binding Phospholipid Binding Heparin Binding Lipid Binding Identical Protein Binding Lipoprotein Lipase Activator Activity	Magnesium Ion Binding GTPase Activity Calcium Channel Regulator Activity Protein Binding Calmodulin Binding GTP Binding GDP Binding
	Biological Process	Negative Regulation Of Endothelial Cell Proliferation Platelet Degranulation Triglyceride Metabolic Process Blood Coagulation, Intrinsic Pathway Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Positive Regulation Of Blood Coagulation Negative Regulation Of Blood Coagulation Plasminogen Activation Negative Regulation Of Myeloid Cell Apoptotic Process Triglyceride Transport Negative Regulation Of Smooth Muscle Cell Apoptotic Process Positive Regulation Of Lipoprotein Lipase Activity Regulation Of Fibrinolysis Negative Regulation Of Fibrinolysis	Mitotic Cell Cycle Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway Chromosome Organization Metaphase Plate Congression Negative Regulation Of High Voltage-gated Calcium Channel Activity
Pathways		Platelet degranulation
Drugs		LJP 1082 Copper
Diseases
GWAS		β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374) Activated partial thromboplastin time ( 29403010) Blood pressure measurement (high sodium and potassium intervention) ( 24165912) Blood protein levels ( 30072576 29875488 28240269) Cardiometabolic and hematological traits ( 27668658) Coronary artery disease ( 29212778) Creatine kinase levels ( 29403010) LDL cholesterol ( 24097068 30275531) LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Platelet count ( 27863252) Plateletcrit ( 27863252) Presence of antiphospholipid antibodies ( 27098658) Systolic blood pressure ( 30224653) Triglycerides ( 30275531)	Carotid plaque burden ( 28282560) Coronary artery disease ( 29212778) Pulse pressure ( 30578418)
Interacting Genes		14 interacting genes: AKT1 ANXA2 CDC42 CLEC4G F10 F12 GEM GRB2 LPA LRP2 LRP8 PLG RBBP6 TP53	41 interacting genes: A2M AHCYL1 APOH BLZF1 BMP1 CALM1 CCDC102B CLDN15 CLEC4G COG8 CTSL DEUP1 GMIP GOLGA2 IKZF3 INO80E KCTD9 KLC3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 LZTS2 NDUFAF3 NDUFS8 NOTCH2NLA PDLIM7 PNMA1 RNF7 RUNDC3A SDHB SSX2IP TCF4 TFIP11 TRAF1 TRIM23 TRIM27 TRIM54 VTN YBEY YWHAB
Entrez ID		350	2669
HPRD ID		00728	11553
Ensembl ID		ENSG00000091583	ENSG00000164949
Uniprot IDs		A0A384NKM6 P02749	A0A024R9F5 P55040
PDB IDs		1C1Z 1G4F 1G4G 1QUB 2KRI 3OP8 4JHS	2CJW 2G3Y 2HT6
Enriched GO Terms of Interacting Partners?
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