FAM131C and SFI1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FAM131C	SFI1
Description		family with sequence similarity 131 member C	SFI1 centrin binding protein
Image		No pdb structure
GO Annotations	Cellular Component		Centrosome Centriole Cytosol
	Molecular Function	Protein Binding	Protein Binding Phosphatase Binding
	Biological Process		G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Phosphatase Activity Ciliary Basal Body-plasma Membrane Docking
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Cognitive performance ( 19734545) Normal facial asymmetry (angle of surface orientation score) ( 30631343)	Age-related hearing impairment ( 24939585) Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Metabolite levels ( 23823483) Type 2 diabetes ( 31118516)
Interacting Genes		10 interacting genes: APP DNAJA3 EWSR1 GRN HPCAL4 LMO3 MAD1L1 NDN SFI1 VSNL1	14 interacting genes: CCDC120 CCDC57 CETN2 CRX FAM131C GCSH GOLGA2 KRT19 LPXN MAD2L2 MDFI RADIL RBPMS SERTAD1
Entrez ID		348487	9814
HPRD ID		08779	11550
Ensembl ID		ENSG00000185519	ENSG00000198089
Uniprot IDs		Q96AQ9	A8K8P3
PDB IDs			2K2I
Enriched GO Terms of Interacting Partners?
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