HOXC8 and BTG2

Number of citations of the paper that reports this interaction (PubMedID 10617598)
41

Data Source:
HPRD (in vitro)

		HOXC8	BTG2
Description		homeobox C8	BTG anti-proliferation factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm Microtubule Cytoskeleton	Nucleus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific DNA Binding	DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Neuron Differentiation Skeletal System Morphogenesis	Negative Regulation Of Transcription By RNA Polymerase II DNA Repair Protein Methylation Cellular Response To DNA Damage Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Negative Regulation Of Cell Proliferation Associative Learning Response To Mechanical Stimulus Anterior/posterior Pattern Specification Response To Organic Cyclic Compound Negative Regulation Of Translation Dentate Gyrus Development Central Nervous System Neuron Development Neuron Projection Development Skeletal Muscle Cell Differentiation Response To Peptide Hormone Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Mitotic Cell Cycle Response To Electrical Stimulus Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Neural Precursor Cell Proliferation
Pathways			TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Immature fraction of reticulocytes ( 27863252) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Red blood cell count ( 27863252) Red cell distribution width ( 27863252 28957414)
Interacting Genes		12 interacting genes: BMPR1A BTG2 DLX2 DLX5 GMNN HOMEZ JUN MSX1 RBPMS SMAD1 SMAD4 SMAD6	11 interacting genes: CNOT7 CNOT8 HOXB9 HOXC8 PICK1 PRKCA PRMT1 SKP2 SMAD1 SMAD9 SRA1
Entrez ID		3224	7832
HPRD ID		00856	03357
Ensembl ID		ENSG00000037965	ENSG00000159388
Uniprot IDs		P31273	P78543
PDB IDs			3DJU 3E9V
Enriched GO Terms of Interacting Partners?
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