HOXA11 and YY1

Number of citations of the paper that reports this interaction (PubMedID 16963455)
12

Data Source:
BioGRID (pull down, affinity chromatography technology)

		HOXA11	YY1
Description		homeobox A11	YY1 transcription factor
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Factor Complex Protein-containing Complex Protein-DNA Complex	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Nuclear Matrix Ino80 Complex PcG Protein Complex Ribonucleoprotein Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific DNA Binding	Four-way Junction DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Coactivator Activity Transcription Corepressor Activity RNA Binding Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding SMAD Binding Promoter-specific Chromatin Binding
	Biological Process	Skeletal System Development Metanephros Development Branching Involved In Ureteric Bud Morphogenesis Organ Induction Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Spermatogenesis Single Fertilization Mesodermal Cell Fate Specification Male Gonad Development Anatomical Structure Morphogenesis Anterior/posterior Pattern Specification Dorsal/ventral Pattern Formation Proximal/distal Pattern Formation Positive Regulation Of Cell Development Embryonic Limb Morphogenesis Positive Regulation Of Chondrocyte Differentiation Embryonic Forelimb Morphogenesis Embryonic Digit Morphogenesis Positive Regulation Of Transcription, DNA-templated Developmental Growth Uterus Development Embryonic Skeletal Joint Morphogenesis Cartilage Development Involved In Endochondral Bone Morphogenesis	Negative Regulation Of Transcription By RNA Polymerase II Double-strand Break Repair Via Homologous Recombination Regulation Of Transcription By RNA Polymerase II RNA Localization Cellular Response To DNA Damage Stimulus Spermatogenesis Anterior/posterior Pattern Specification Response To UV-C Gene Expression Negative Regulation Of Gene Expression Protein Deubiquitination Cell Differentiation Negative Regulation Of Interferon-beta Production Cellular Response To UV Response To Prostaglandin F Positive Regulation Of Transcription By RNA Polymerase II Camera-type Eye Morphogenesis Chromosome Organization Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Cellular Response To Interleukin-1 Negative Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Pathways			Activation of anterior HOX genes in hindbrain development during early embryogenesis UCH proteinases DNA Damage Recognition in GG-NER TFAP2 (AP-2) family regulates transcription of growth factors and their receptors Estrogen-dependent gene expression
Drugs
Diseases		Radioulnar synostosis with amegakaryocytic thrombocytopenia
GWAS		Heel bone mineral density ( 30598549 28869591) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412 28448500) Waist-hip ratio ( 25673412) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)	Estimated glomerular filtration rate ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Pulse pressure ( 30224653)
Interacting Genes		5 interacting genes: CREBBP GMNN MEIS1 PGBD3 YY1	57 interacting genes: APP ATF2 ATF6 ATF7 AURKA BAP1 BCCIP BRCA1 CDKN2A CREB1 CRKL DNMT3L E2F2 E2F3 EED EP300 FKBP1A FKBP3 GRN GTF2I HCFC1 HDAC2 HDAC3 HOXA11 INO80 KAT2B MTA2 MYC NEDD4L NFKB1 NOTCH1 NPM1 NR1H2 PPIA PSMD9 RAF1 RUVBL1 RUVBL2 RYBP SAP30 SKP2 SLC39A7 SMAD1 SMAD2 SMAD3 SMURF2 SP1 SPRY1 SREBF1 TESK1 TFCP2 TP53 TWIST1 UHRF2 YAF2 ZNF232 ZRANB2
Entrez ID		3207	7528
HPRD ID		00846	02482
Ensembl ID		ENSG00000005073	ENSG00000100811
Uniprot IDs		P31270	P25490
PDB IDs			1UBD 1ZNM 4C5I
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?