HLA-DRB3 and CDCA8

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		HLA-DRB3	CDCA8
Description		major histocompatibility complex, class II, DR beta 3	cell division cycle associated 8
Image
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane ER To Golgi Transport Vesicle Membrane Membrane Transport Vesicle Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Late Endosome Membrane Trans-Golgi Network Membrane MHC Class II Protein Complex Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane	Chromosome, Centromeric Region Cell Nucleoplasm Nucleolus Cytosol Chromocenter Midbody Chromosome Passenger Complex Protein-containing Complex Intercellular Bridge Spindle Midzone
	Molecular Function	MHC Class II Receptor Activity Peptide Antigen Binding	Protein Binding
	Biological Process	Adaptive Immune Response Signal Transduction Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II T Cell Receptor Signaling Pathway Interferon-gamma-mediated Signaling Pathway	Mitotic Sister Chromatid Segregation Mitotic Metaphase Plate Congression Chromosome Organization Cell Division
Pathways		Downstream TCR signaling Phosphorylation of CD3 and TCR zeta chains Translocation of ZAP-70 to Immunological synapse Generation of second messenger molecules MHC class II antigen presentation PD-1 signaling Interferon gamma signaling	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA replication proteins RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Plantar warts ( 28928442)	Axial length ( 24144296) Eyebrow thickness ( 26926045)
Interacting Genes		4 interacting genes: CDCA8 CTAG1B MAP3K13 POMC	14 interacting genes: AURKB BIRC5 H3C14 HLA-DRB3 INCENP MAPKAPK5 NEK3 PIAS2 RANBP2 SENP3 SGO1 SGO2 TTK UBE2I
Entrez ID		3125	55143
HPRD ID		09985	13017
Ensembl ID			ENSG00000134690
Uniprot IDs		A0A4D6G1L1 P79483	Q53HL2
PDB IDs		2Q6W 3C5J 4H1L	2KDD 2QFA 2RAW 2RAX
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?