ANXA5 and COL10A1

Number of citations of the paper that reports this interaction (PubMedID 1397263)
13

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		ANXA5	COL10A1
Description		annexin A5	collagen type X alpha 1 chain
Image
GO Annotations	Cellular Component	Extracellular Region Intracellular Cytoplasm Cytosol Focal Adhesion External Side Of Plasma Membrane Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Endothelial Microparticle	Extracellular Region Collagen Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Phospholipase Inhibitor Activity Calcium Ion Binding Protein Binding Phospholipid Binding Calcium-dependent Phospholipid Binding	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength Metal Ion Binding
	Biological Process	Platelet Degranulation Signal Transduction Blood Coagulation Negative Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Calcium Ion Transmembrane Transport	Skeletal System Development Extracellular Matrix Organization
Pathways		Platelet degranulation	Collagen degradation Collagen degradation Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Non-integrin membrane-ECM interactions Collagen chain trimerization
Drugs		L-Alpha-Glycerophosphorylserine L-thioproline K201 L-Alpha-Glycerophosphorylethanolamine 1,4-Dideoxy-O2-Sulfo-Glucuronic Acid N,O6-Disulfo-Glucosamine 1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid Copper
Diseases			Metaphyseal dysplasias, including: Metaphyseal dysplasia, Schmid type; Metaphyseal dysplasia, McKusik type; Metaphyseal dysplasia, Jansen type; Shwachman-Bodian-Diamond syndrome (SBDS); Metaphyseal anadysplasia (MAD)
GWAS		Age at smoking initiation in chronic obstructive pulmonary disease ( 21685187) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Resting-state electroencephalogram vigilance ( 29703947)	Age-related macular degeneration ( 23455636 21665990) Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042) Myopia ( 27182965) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		17 interacting genes: ACTG1 APP COL10A1 COL2A1 EED EIF4G1 FDFT1 IFNGR2 ITGB5 KDR LAMC3 PPP2R1B SUPT4H1 TERF1 TERF2 TERF2IP TINF2	4 interacting genes: ANXA5 BANP P4HB UBQLN1
Entrez ID		308	1300
HPRD ID		00568	00357
Ensembl ID		ENSG00000164111	ENSG00000123500
Uniprot IDs		P08758 V9HWE0	Q03692
PDB IDs		1ANW 1ANX 1AVH 1AVR 1HAK 1HVD 1HVE 1HVF 1HVG 1SAV 2XO2 2XO3	1GR3
Enriched GO Terms of Interacting Partners?
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