H2AX and HUWE1

  • Number of citations of the paper that reports this interaction (PubMedID 27146073)
  • 14
  • Data Source:
  • BioGRID (enzymatic study)

H2AX

HUWE1

Description H2A.X variant histone HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes 47 interacting genes: A2M ACTB ALG9 ATM ATR BARD1 BMI1 BRCA1 BRCA2 BRD1 CALM1 COPG1 DDX21 DHX9 EYA1 HUWE1 KAT5 MASP1 MDC1 MRE11 NBN NCL NGFR OTUB1 PAXIP1 PBK PPP1CA PRKDC PTPA QARS1 RNF168 RNF8 RPS6KA3 SMARCA4 SSRP1 SUPT16H SUPT5H TAF1C TAF5L TERF2 TIAM2 TOPORS TP53BP1 TRAF6 TSSK6 USP11 WRN 35 interacting genes: ABL1 ATOH1 CALM1 CCL1 CDKN2A CTNNB1 CUL4B ERG H2AX HDAC2 HSPB1 LAPTM5 MCL1 MYCN PCNA PIAS2 POLB POLL PPP5C RBBP7 RNF11 SMAD2 SMAD9 TBP TNS2 TP53 UBC UBE2D1 UBE2D2 UBE2D3 UBE2G1 UBE2L3 USP4 USP7 WBP2
Entrez ID 3014 10075
HPRD ID 03465 06608
Ensembl ID ENSG00000188486 ENSG00000086758
Uniprot IDs P16104 A0A024R9W5 Q7Z6Z7
PDB IDs 1YDP 2AZM 2D31 2DYP 3SHV 3SQD 3SZM 3U3Z 2EKK 2MUL 3G1N 3H1D 5C6H 5LP8 6FYH 6MIW 6PFL
Enriched GO Terms of Interacting Partners?
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