NCAPH2 and FOLR1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		NCAPH2	FOLR1
Description		non-SMC condensin II complex subunit H2	folate receptor alpha
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Condensin Complex Nucleus Nucleoplasm Membrane Cell Junction Intercellular Bridge	Golgi Membrane Nucleus Endosome Endoplasmic Reticulum Membrane Plasma Membrane Cell Surface ER To Golgi Transport Vesicle Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Transport Vesicle Clathrin-coated Vesicle Anchored Component Of External Side Of Plasma Membrane Brush Border Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Extracellular Exosome
	Molecular Function	Chromatin Binding Protein Binding	Folic Acid Binding Drug Binding Signaling Receptor Activity Methotrexate Binding Folic Acid Receptor Activity
	Biological Process	Mitotic Chromosome Condensation Meiotic Chromosome Condensation T Cell Differentiation In Thymus Chromosome Organization Mitotic Sister Chromatid Separation Female Meiosis Chromosome Separation	Heart Looping Neural Crest Cell Migration Involved In Heart Formation Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis ER To Golgi Vesicle-mediated Transport Receptor-mediated Endocytosis Folic Acid Transport Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Axon Regeneration Folic Acid Metabolic Process COPII Vesicle Coating Regulation Of Canonical Wnt Signaling Pathway Pharyngeal Arch Artery Morphogenesis Anterior Neural Tube Closure Cellular Response To Folic Acid Folate Import Across Plasma Membrane
Pathways		Condensation of Prophase Chromosomes	COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport
Drugs			Folic Acid Vintafolide Farletuzumab
Diseases
GWAS		B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Cerebrospinal fluid clusterin levels ( 26545630) Chronic lymphocytic leukemia ( 28165464) Mean corpuscular hemoglobin ( 20139978) Red blood cell traits ( 23222517)
Interacting Genes		11 interacting genes: ACTN2 EGLN3 FOLR1 LMO2 PRPF31 SNRPC TRAF2 TTC25 TTC32 TUBB USHBP1	5 interacting genes: CUL3 INTS4 IRAK3 LYN NCAPH2
Entrez ID		29781	2348
HPRD ID		11783	00638
Ensembl ID		ENSG00000025770	ENSG00000110195
Uniprot IDs		Q6IBW4	A0A024R5H1 P15328
PDB IDs			4KM6 4KM7 4KMX 4LRH 5IZQ
Enriched GO Terms of Interacting Partners?
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