GTF2F2 and TAF5

Number of citations of the paper that reports this interaction (PubMedID 8758937)
43

Data Source:
HPRD (in vitro)

		GTF2F2	TAF5
Description		general transcription factor IIF subunit 2	TATA-box binding protein associated factor 5
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor TFIIF Complex Microtubule Cytoskeleton Transcriptional Preinitiation Complex	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor TFIID Complex Nucleolus Actin Cytoskeleton Transcription Factor TFTC Complex
	Molecular Function	DNA Binding DNA Helicase Activity Protein Binding ATP Binding	Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Identical Protein Binding Transcription Regulatory Region DNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Fibroblast Growth Factor Receptor Signaling Pathway RNA Metabolic Process DNA Duplex Unwinding Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter SnRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Viral Transcription Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter	DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Viral Process SnRNA Transcription By RNA Polymerase II Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex RNA Pol II CTD phosphorylation and interaction with CE during HIV infection HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation Viral Messenger RNA Synthesis RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes FGFR2 alternative splicing RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes mRNA Capping mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Elongation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Pol II CTD phosphorylation and interaction with CE Signaling by FGFR2 IIIa TM Estrogen-dependent gene expression	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Normal facial asymmetry (angle of surface orientation score) ( 30631343) Type 2 diabetes ( 25760438)	Autism spectrum disorder or schizophrenia ( 28540026) Height ( 31562340) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Schizophrenia ( 25056061 23974872)
Interacting Genes		30 interacting genes: AHR AR ARNT ATF2 ATF4 CEBPG CREB1 FOS GTF2B GTF2E1 GTF2E2 GTF2F1 HMGA1 HTATSF1 JUN KLF5 MSX2 MYC POLR2A POLR2E RBPMS RPL27A TAF5 TBP TCEA1 TCTEX1D2 TRAM2 TSC22D1 TSPAN3 URI1	16 interacting genes: CPSF1 GTF2F2 H3-4 TAF1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF6 TAF7 TAF8 TAF9 TBP UBE2I
Entrez ID		2963	6877
HPRD ID		01804	11876
Ensembl ID		ENSG00000188342	ENSG00000148835
Uniprot IDs		A0A024RDU9 P13984	Q15542
PDB IDs		1BBY 1F3U 2BBY 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 6O9L	2NXP 6F3T 6MZC 6MZD 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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