GTF2E2 and MCC

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		GTF2E2	MCC
Description		general transcription factor IIE subunit 2	MCC regulator of WNT signaling pathway
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GO Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIE Complex Cytosol Nuclear Speck	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Lamellipodium Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	DNA Binding RNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity	Protein Binding Signaling Receptor Activity
	Biological Process	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter SnRNA Transcription By RNA Polymerase II	Signal Transduction Negative Regulation Of Epithelial Cell Migration Wnt Signaling Pathway Establishment Of Protein Localization Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Cognitive performance ( 20125193) Metabolite levels (X-11787) ( 23934736)	Brain cytoarchitecture ( 20308991) Cerebral amyloid angiopathy ( 25188341) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Height ( 31562340) Metabolite levels ( 23823483) Neurofibrillary tangles ( 31497858)
Interacting Genes		23 interacting genes: APP ATF7IP CCNH CDK7 ERCC3 ERCC6 FOS GTF2A1 GTF2B GTF2E1 GTF2F1 GTF2F2 GTF2H1 JUN KLF5 MCC MDM2 MNAT1 NUP62 SND1 SUPT16H TBP XPA	10 interacting genes: APP CBX5 CSNK1E DYNC1I1 ERBIN GTF2E2 MTNR1A NEK2 NFKBIB STOML2
Entrez ID		2961	4163
HPRD ID		01800	01157
Ensembl ID		ENSG00000197265	ENSG00000171444
Uniprot IDs		P29084	P23508
PDB IDs		1D8J 1D8K 5GPY 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 6O9L	6MTU
Enriched GO Terms of Interacting Partners?
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