PDIA3 and SLC2A1

Number of citations of the paper that reports this interaction (PubMedID 9153243)
17

Data Source:
BioGRID (pull down)
HPRD (in vivo)

		PDIA3	SLC2A1
Description		protein disulfide isomerase family A member 3	solute carrier family 2 member 1
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GO Annotations	Cellular Component	Extracellular Space Cell Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Lumen Focal Adhesion Cell Surface Melanosome MHC Class I Peptide Loading Complex Phagocytic Vesicle Recycling Endosome Membrane Extracellular Exosome	Golgi Membrane Female Pronucleus Cytosol Plasma Membrane Integral Component Of Plasma Membrane Caveola Intercalated Disc Membrane Basolateral Plasma Membrane Apical Plasma Membrane Z Disc Midbody Cortical Actin Cytoskeleton Sarcolemma Melanosome Extracellular Exosome Blood Microparticle Presynapse
	Molecular Function	RNA Binding Protein Disulfide Isomerase Activity Cysteine-type Endopeptidase Activity Phospholipase C Activity Protein Binding Disulfide Oxidoreductase Activity Peptide Disulfide Oxidoreductase Activity Identical Protein Binding	Glucose Transmembrane Transporter Activity Protein Binding Kinase Binding Dehydroascorbic Acid Transmembrane Transporter Activity Identical Protein Binding Xenobiotic Transmembrane Transporter Activity Protein Self-association D-glucose Transmembrane Transporter Activity
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Protein Folding Proteolysis Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis Oxidation-reduction Process Cellular Response To Interleukin-7 Positive Regulation Of Extrinsic Apoptotic Signaling Pathway	Response To Hypoxia Lactose Biosynthetic Process Female Pregnancy Regulation Of Glucose Transmembrane Transport L-ascorbic Acid Metabolic Process Cerebral Cortex Development Response To Insulin Cellular Response To Glucose Starvation Xenobiotic Transport Regulation Of Insulin Secretion Protein-containing Complex Assembly Dehydroascorbic Acid Transport Cellular Response To Mechanical Stimulus Cellular Hyperosmotic Response Response To Thyroglobulin Triiodothyronine Glucose Transmembrane Transport
Pathways		ER-Phagosome pathway ER-Phagosome pathway Calnexin/calreticulin cycle Antigen Presentation: Folding, assembly and peptide loading of class I MHC Antigen Presentation: Folding, assembly and peptide loading of class I MHC	Cellular hexose transport Vitamin C (ascorbate) metabolism Regulation of insulin secretion Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1) Lactose synthesis
Drugs		Zinc Copper	Resveratrol
Diseases			GLUT1 deficiency syndrome (GLUT1DS); Glucose transport defect of the blood-brain barrier Primary torsion dystonia (PTD)
GWAS		Blood protein levels ( 30072576) Lead levels ( 26025379)	Birth weight ( 31043758) Cardiac hypertrophy ( 21348951) Monocyte count ( 27863252) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		20 interacting genes: APP BACE1 CALR CANX ERO1A ERP27 ESR1 FBLN5 GYPC HLA-A IFNG LGALS9 MDM2 MTNR1B SLC12A3 SLC2A1 STAT3 SUMO4 TAP1 UBE3A	13 interacting genes: CALR CANX COPS6 GAPDH GIPC1 HSPB2 PDIA3 PTK2B SNX27 STOM SUMO1 UBE2I VHL
Entrez ID		2923	6513
HPRD ID		03625	00683
Ensembl ID		ENSG00000167004	ENSG00000117394
Uniprot IDs		P30101 V9HVY3	P11166 Q59GX2
PDB IDs		2ALB 2DMM 2H8L 3F8U 6ENY	1SUK 4PYP 5EQG 5EQH 5EQI
Enriched GO Terms of Interacting Partners?
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