SETD2 and SPOP

  • Number of citations of the paper that reports this interaction (PubMedID 28805822)
  • 37
  • Data Source:
  • BioGRID (two hybrid)

SETD2

SPOP

Description SET domain containing 2, histone lysine methyltransferase speckle type BTB/POZ protein
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Granulocyte percentage of myeloid white cells ( 27863252)
  • HDL cholesterol ( 24097068 30275531)
  • HDL cholesterol levels ( 28334899)
  • Huntington's disease progression ( 28642124)
  • Lymphocyte counts ( 27863252)
  • Lymphocyte percentage of white cells ( 27863252)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Monocyte count ( 27863252)
  • Monocyte percentage of white cells ( 27863252)
  • Platelet distribution width ( 27863252)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
  • White blood cell count ( 27863252)
  • White blood cell count (basophil) ( 27863252)
Interacting Genes 8 interacting genes: ATXN1 CIC H3-4 H3C1 HTT SIAH2 SMAD3 SPOP 69 interacting genes: AEN AMOTL2 AR BRD2 BRD3 BRD4 BRMS1 CACUL1 CAPRIN1 CBX4 CCNE1 CDK4 CHAF1A CHD3 CREB5 CTDSPL2 CUL3 DAXX DDIT3 DHX15 DPPA2 EGLN2 ERF ERG FAF1 GATAD2A GCC1 GCC2 GIT2 GLI2 GLI3 GMEB1 HCST HMGCS1 INF2 KPNA5 LRCH4 MACROH2A1 MRE11 MYD88 NANOG NCOA3 NUDCD3 PDX1 PIAS1 PIAS3 RANBP9 RBFOX2 RBPJ RPRD2 RTN3 RXRB SETD2 SRRM1 SUMO1 TCOF1 TOPORS TRAF1 TRAF6 UBE2D1 UBE2D2 UBE2E3 UBE2I UBE2L3 VPS9D1-AS1 YWHAG ZBTB16 ZCCHC12 ZMYND8
Entrez ID 29072 8405
HPRD ID 11043 16004
Ensembl ID ENSG00000181555 ENSG00000121067
Uniprot IDs Q9BYW2 O43791
PDB IDs 2A7O 2MDC 2MDI 2MDJ 4FMU 4H12 5JJY 5JLB 5JLE 5LSS 5LSX 5LSY 5LSZ 5LT6 5LT7 5LT8 5V21 5V22 2CR2 3HQH 3HQI 3HQL 3HQM 3HSV 3HTM 3HU6 3IVB 3IVQ 3IVV 4EOZ 4HS2 4J8Z 4O1V 6F8F 6F8G 6I41 6I5P 6I68 6I7A
Enriched GO Terms of Interacting Partners?
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