NOB1 and UPF2

Number of citations of the paper that reports this interaction (PubMedID 15231747)
56

Data Source:
HPRD (two hybrid)

		NOB1	UPF2
Description		NIN1 (RPN12) binding protein 1 homolog	UPF2 regulator of nonsense mediated mRNA decay
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Preribosome, Small Subunit Precursor	Nucleus Cytoplasm Cytosol Polysome Exon-exon Junction Complex Cytoplasmic Ribonucleoprotein Granule Perinuclear Region Of Cytoplasm
	Molecular Function	Endoribonuclease Activity Metal Ion Binding	RNA Binding Protein Binding Telomeric DNA Binding
	Biological Process	Cleavage Involved In RRNA Processing RRNA Processing Visual Perception Maturation Of SSU-rRNA RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Liver Development MRNA Export From Nucleus Animal Organ Regeneration
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Blood osmolality (transformed sodium) ( 28360221) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body mass index ( 26426971) Smoking status (ever vs never smokers) ( 30643258) Systolic blood pressure ( 30578418)	Diverticular disease ( 30177863)
Interacting Genes		3 interacting genes: APP PRNP UPF2	75 interacting genes: ABCF2 AGPAT1 ART4 ATP1B3 BLM CALR CENPU CIZ1 COMTD1 CYBA DCP1B DCP2 DPF2 E4F1 EIF1 EIF4A1 EIF4G1 ENO1 EXOSC1 EXOSC10 EXOSC4 EXOSC6 EXOSC8 GADD45GIP1 HBZ HMGA1 HS3ST3A1 HSF2BP ITGB1 KRT18 LDHA LSM1 MAP1A MAP1LC3B MIF MRPL40 MTERF3 MTREX MYB NDUFA7 NOB1 NOMO1 NOP53 PHB2 PITX1 PUF60 RNPS1 RPL13 RPL5 RPL8 RPS15 RPS25 RPS6 RPS7 RRP7A RSRC2 SERBP1 SERF2 SMG1 SUMO3 TK1 TNNI2 TOP3B TUBB2A TYMS UPF1 UPF3B WNK1 XRN1 XRN2 ZBTB48 ZFP36 ZGPAT ZNF408 ZNF44
Entrez ID		28987	26019
HPRD ID		11395	10405
Ensembl ID		ENSG00000141101	ENSG00000151461
Uniprot IDs		Q9ULX3	Q9HAU5
PDB IDs		6G18 6G4S 6G51 6G53 6G5I	1UW4 2WJV 4CEK 4CEM
Enriched GO Terms of Interacting Partners?
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