OSTM1 and CLCN7

Number of citations of the paper that reports this interaction (PubMedID 16525474)
87

Data Source:
HPRD (in vivo)

		OSTM1	CLCN7
Description		osteoclastogenesis associated transmembrane protein 1	chloride voltage-gated channel 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Cytosol Integral Component Of Membrane	Nucleoplasm Lysosomal Membrane Membrane Integral Component Of Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle
	Molecular Function		Voltage-gated Chloride Channel Activity Chloride Channel Activity ATP Binding Chloride Transmembrane Transporter Activity Antiporter Activity Transmembrane Transporter Activity
	Biological Process	Osteoclast Differentiation Ion Transmembrane Transport	Response To PH Ion Transmembrane Transport Chloride Transmembrane Transport
Pathways		Stimuli-sensing channels	Stimuli-sensing channels
Drugs
Diseases		Osteopetrosis, including: Osteopetrosis, severe neonatal or infantile forms; Osteopetrosis, intermediate forms; Osteopetrosis with renal tubular acidosis; Osteopetrosis, late-onset form type 1; Osteopetrosis, late-onset form type 2; Osteopetrosis, osteoclast poor	Osteopetrosis, including: Osteopetrosis, severe neonatal or infantile forms; Osteopetrosis, intermediate forms; Osteopetrosis with renal tubular acidosis; Osteopetrosis, late-onset form type 1; Osteopetrosis, late-onset form type 2; Osteopetrosis, osteoclast poor
GWAS		Major depressive disorder ( 29187746)
Interacting Genes		6 interacting genes: CLCN7 GPSM1 LIG4 RGS17 RGS19 RGS20	5 interacting genes: CREB3 LMNA MTDH OSTM1 PACS1
Entrez ID		28962	1186
HPRD ID		09628	04103
Ensembl ID		ENSG00000081087	ENSG00000103249
Uniprot IDs		Q86WC4	P51798
PDB IDs
Enriched GO Terms of Interacting Partners?
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