CCDC57 and RNF6

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		CCDC57	RNF6
Description		coiled-coil domain containing 57	ring finger protein 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm PML Body Axon Nuclear Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	DNA Binding Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Androgen Receptor Binding Ubiquitin Protein Ligase Activity
	Biological Process		Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Axon Extension Protein K27-linked Ubiquitination Positive Regulation Of Transcription, DNA-templated Regulation Of Androgen Receptor Signaling Pathway Protein K48-linked Ubiquitination Protein K6-linked Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Blood metabolite levels ( 24816252) Blood urea nitrogen levels ( 31152163) Proteinuria and chronic kidney disease ( 26420894)	Sporadic pituitary adenoma ( 26029870) Type 2 diabetes ( 24509480 30297969 30718926 28869590) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		46 interacting genes: AQP1 ARL4A AXIN1 CBX8 CCDC120 CDC20B CEP57L1 CWF19L2 ECPAS FAM161A FAM50B FAM90A1 GPKOW HAUS1 HBA2 LENG1 LINC00526 MFAP1 NAPRT NELFE NUMA1 PER1 PPHLN1 PPP1R18 PRAM1 PRPF31 PRR3 PTPN7 RAB3IL1 RNF6 ROBO3 RXRB SFI1 SIRPA TBC1D22B TLE5 TMEM100 TSGA10IP USP15 USP2 UTP14C ZFC3H1 ZGPAT ZMAT2 ZNF417 ZNF688	36 interacting genes: AHCYL1 AR CBY2 CCDC33 CCDC57 CEP70 GOLGA2 HOOK2 IKZF1 IKZF3 KIAA0753 KRT15 KRT40 LDOC1 MAGED1 MDFI MEOX2 MID2 MIPOL1 MTUS2 PNMA2 REL RINT1 RPGRIP1 SSX2IP STX11 TADA2A TCF4 TFIP11 TNS2 TRIM23 TRIM27 TRIM37 TSGA10 UBE2D1 UBE2H
Entrez ID		284001	6049
HPRD ID		14150	05027
Ensembl ID		ENSG00000176155	ENSG00000127870
Uniprot IDs		A0A590UJT6 Q2TAC2	A0A024RDP2 A0A0S2Z4G9 Q9Y252
PDB IDs
Enriched GO Terms of Interacting Partners?
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