P4HA3 and SERTAD1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		P4HA3	SERTAD1
Description		prolyl 4-hydroxylase subunit alpha 3	SERTA domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen	Nucleus Cytoplasm
	Molecular Function	Procollagen-proline 4-dioxygenase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen L-ascorbic Acid Binding	Protein Binding
	Biological Process	Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Oxidation-reduction Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Proliferation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Collagen biosynthesis and modifying enzymes
Drugs
Diseases
GWAS		Hippocampal atrophy ( 25625606)	Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927)
Interacting Genes		11 interacting genes: DTNBP1 HGS MAGEA2B MAGEC2 MEOX2 NDN NUTM1 P4HB SERTAD1 WDR62 ZC3H12A	39 interacting genes: ADCY1 ASB8 ATXN7L3 CCND2 CDK4 CDKN2A CHURC1 CIB3 COPB1 CREBBP DENND4A EGLN3 ELOC EP300 FAH HIVEP1 HSPB1 KAT2B KLHL42 MVP NEDD4 P4HA3 PATE1 POT1 PRDM4 RBX1 RCHY1 ROPN1 SETD7 SFI1 SMAD3 SPEN STAT5B SUPT7L TGM2 TLR4 TRIM28 XIAP ZNF410
Entrez ID		283208	29950
HPRD ID		16413	15326
Ensembl ID		ENSG00000149380	ENSG00000197019
Uniprot IDs		Q7Z4N8	Q53GC0 Q9UHV2
PDB IDs
Enriched GO Terms of Interacting Partners?
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