GPD2 and ALDOA

Number of citations of the paper that reports this interaction (PubMedID 2065091)
4

Data Source:
HPRD (in vitro)

		GPD2	ALDOA
Description		glycerol-3-phosphate dehydrogenase 2	aldolase, fructose-bisphosphate A
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Glycerol-3-phosphate Dehydrogenase Complex	Extracellular Region Extracellular Space Cell Nucleus Cytosol Actin Cytoskeleton Membrane Platelet Alpha Granule Lumen M Band I Band Secretory Granule Lumen Sperm Head Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Glycerol-3-phosphate Dehydrogenase (quinone) Activity Calcium Ion Binding Sn-glycerol-3-phosphate:ubiquinone-8 Oxidoreductase Activity	RNA Binding Actin Binding Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding Tubulin Binding Identical Protein Binding Cadherin Binding Fructose Binding
	Biological Process	Glycerol-3-phosphate Metabolic Process Gluconeogenesis Glycerophosphate Shuttle Glycerol Catabolic Process Multicellular Organism Growth Camera-type Eye Development	Platelet Degranulation Fructose Metabolic Process Gluconeogenesis Glycolytic Process ATP Biosynthetic Process Striated Muscle Contraction Actin Filament Organization Binding Of Sperm To Zona Pellucida Regulation Of Cell Shape Fructose 1,6-bisphosphate Metabolic Process Neutrophil Degranulation Muscle Cell Cellular Homeostasis Protein Homotetramerization Canonical Glycolysis
Pathways		Synthesis of PA Triglyceride catabolism	Platelet degranulation Neutrophil degranulation Glycolysis Gluconeogenesis
Drugs			Zinc 1,6-Fructose Diphosphate (Linear Form) Dihydroxyacetone phosphate 1,6-DI-O-PHOSPHONO-D-MANNITOL N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE
Diseases
GWAS		Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Depression ( 29700475) Diisocyanate-induced asthma ( 25918132) Familial squamous cell lung carcinoma ( 29924316) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Motion sickness ( 25628336) Myopia ( 27182965) Possible neuropathic pain in post total joint replacement surgery for osteoarthritis ( 28051079) Response to statin therapy ( 20339536) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Ulcerative colitis ( 25082827) Urinary albumin-to-creatinine ratio ( 31630189)	Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Schizophrenia ( 25056061 29483656)
Interacting Genes		1 interacting genes: ALDOA	26 interacting genes: ADRB2 ALDOB ATP6V1E1 BCAT2 CACNA1A CYTH2 DYNLL1 EGFR FANCA GALNT6 GPD2 HSD17B10 HSPB2 IFNA4 MLH1 MYOC PCNA PIAS4 PLD2 SRPK2 SUMO4 TERF1 TGM2 TRIM63 TUBB XRN1
Entrez ID		2820	226
HPRD ID		00715	00070
Ensembl ID		ENSG00000115159	ENSG00000149925
Uniprot IDs		P43304 Q53T76	P04075 V9HWN7
PDB IDs			1ALD 2ALD 4ALD 5KY6
Enriched GO Terms of Interacting Partners?
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