GOLGA4 and ARL1

Number of citations of the paper that reports this interaction (PubMedID 14580338)
51

Data Source:
BioGRID (x-ray crystallography, pull down, two hybrid)
HPRD (two hybrid, in vivo, in vitro)

		GOLGA4	ARL1
Description		golgin A4	ADP ribosylation factor like GTPase 1
Image
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Extracellular Exosome	Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Trans-Golgi Network Membrane
	Molecular Function	Protein Binding GTPase Binding	GTPase Activity GTP Binding Enzyme Activator Activity Protein Domain Specific Binding Metal Ion Binding
	Biological Process	Vesicle-mediated Transport Golgi To Plasma Membrane Protein Transport Positive Regulation Of Axon Extension	Intracellular Protein Transport Golgi Organization Toxin Metabolic Process Vesicle-mediated Transport Activation Of Phospholipase D Activity Protein Localization To Golgi Apparatus Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport
Pathways		Retrograde transport at the Trans-Golgi-Network Signaling by membrane-tethered fusions of PDGFRA or PDGFRB	Retrograde transport at the Trans-Golgi-Network
Drugs			Guanosine-5'-Diphosphate
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Pulse pressure ( 30578418) Subjective response to lithium treatment ( 26503763)	Lung cancer in never smokers ( 28604730) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
Interacting Genes		8 interacting genes: APP ARL1 ARL3 MACF1 RAB6A SERPINB5 TNIK TRAF3IP1	7 interacting genes: ARFIP2 COPG2 GCC1 GCC2 GOLGA1 GOLGA4 SCOC
Entrez ID		2803	400
HPRD ID		03941	04574
Ensembl ID		ENSG00000144674	ENSG00000120805
Uniprot IDs		Q13439 Q49A56	B4DZG7 P40616
PDB IDs		1R4A 1UPT	1UPT 4DCN 5EE5 5J5C
Enriched GO Terms of Interacting Partners?
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