BEX3 and VTA1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vivo, in vitro)

		BEX3	VTA1
Description		brain expressed X-linked 3	vesicle trafficking 1
Image
GO Annotations	Cellular Component	Nucleus Cytosol	Nucleoplasm Multivesicular Body Cytosol Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Nerve Growth Factor Receptor Binding Protein Binding Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process Identical Protein Binding Metal Ion Binding	Protein Binding Protein C-terminus Binding
	Biological Process	Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Multicellular Organism Development Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process	Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Multivesicular Body Sorting Pathway ESCRT III Complex Disassembly
Pathways		NADE modulates death signalling	Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease ( 30804561) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) FEV1 ( 30804560) Height ( 28552196) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Peak expiratory flow ( 30804560) Retinal vascular caliber ( 21060863)
Interacting Genes		29 interacting genes: AIMP2 AKAP8L CACYBP CCDC116 CCDC85B CTNNBL1 DIABLO EMILIN1 FSD2 GOLGA8EP GOLGA8F MIF MNAT1 NECAB2 NGFR NTRK3 PTPN13 SIVA1 SMPD1 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 TSC1 USHBP1 VTA1 YWHAE	17 interacting genes: APP BEX3 CBS CDK4 CHMP5 DPPA2 KCTD13 KLHL12 LYST MAGEA11 MBIP NBR1 NECAB2 RABAC1 RPIA ZBTB16 ZNRD2
Entrez ID		27018	51534
HPRD ID		02291	09855
Ensembl ID		ENSG00000166681	ENSG00000009844
Uniprot IDs		Q00994	A0A087WY55 Q9NP79
PDB IDs		1SA6	2LXL 2LXM 4TXP 4TXQ 4TXR 4U7E
Enriched GO Terms of Interacting Partners?
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