AP3M1 and TRIM9

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		AP3M1	TRIM9
Description		adaptor related protein complex 3 subunit mu 1	tripartite motif containing 9
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Golgi Apparatus Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Axon Cytoplasm	Cytoplasm Cytoskeleton Synaptic Vesicle Cell Junction Dendrite Presynaptic Cytosol
	Molecular Function	Protein Binding Rab GTPase Binding	SNARE Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein Domain Specific Binding Protein Homodimerization Activity
	Biological Process	Protein Targeting To Lysosome Anterograde Axonal Transport Viral Process Vesicle-mediated Transport Anterograde Synaptic Vesicle Transport	Synaptic Vesicle Exocytosis Protein Ubiquitination Negative Regulation Of SNARE Complex Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Calcium Ion-dependent Exocytosis
Pathways		Association of TriC/CCT with target proteins during biosynthesis	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Cardiac troponin-I levels ( 31014085) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328)	Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Psychosis (atypical) ( 24132900) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		8 interacting genes: AGTRAP AQP4 CRMP1 RUFY1 SIPA1L2 TGOLN2 TRIM14 TRIM9	28 interacting genes: AP3M1 BTRC CHFR CSNK1D CWF19L2 DTNBP1 DTX3L EVL EXOC1 GFM2 LONRF1 MDM2 MNAT1 MUL1 NCF1 NFKBID PCGF3 RNF166 RPL4P5 SNAP25 SPG21 TRIM27 TRIM46 TRIM8 TSSK3 USP2 USP21 VASP
Entrez ID		26985	114088
HPRD ID		16496	05947
Ensembl ID		ENSG00000185009	ENSG00000100505
Uniprot IDs		A0A024QZR5 B4DRN6 Q9Y2T2	Q9C026
PDB IDs			2DB8
Enriched GO Terms of Interacting Partners?
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